2006
Hormonal Regulation of Nuclear Permeability* ♦
O'Brien EM, Gomes DA, Sehgal S, Nathanson MH. Hormonal Regulation of Nuclear Permeability* ♦. Journal Of Biological Chemistry 2006, 282: 4210-4217. PMID: 17158097, PMCID: PMC2835336, DOI: 10.1074/jbc.m606300200.Peer-Reviewed Original ResearchConceptsProtein kinase CNuclear permeabilityGene transcriptionNuclear envelopeSecond messengerKinase CPhotoactivatable green fluorescent proteinCertain G protein-coupled receptorsG protein-coupled receptorsActivate protein kinase CCytosolic Ca2Protein-coupled receptorsGreen fluorescent proteinTargeting sequenceTranscription factorsRegulatory moleculesNuclear membraneFluorescent proteinPassage of moleculesIntranuclear eventsNovel mechanismShort-term regulationHormonal regulationTranscriptionRegulation
2003
Regulation of calcium signals in the nucleus by a nucleoplasmic reticulum
Echevarría W, Leite MF, Guerra MT, Zipfel WR, Nathanson MH. Regulation of calcium signals in the nucleus by a nucleoplasmic reticulum. Nature Cell Biology 2003, 5: 440-446. PMID: 12717445, PMCID: PMC3572851, DOI: 10.1038/ncb980.Peer-Reviewed Original ResearchMeSH KeywordsActive Transport, Cell NucleusCalciumCalcium ChannelsCalcium SignalingCell MembraneCell Nucleus StructuresCytosolEndoplasmic ReticulumEukaryotic CellsHumansInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsMicroscopy, ConfocalNuclear EnvelopePhotochemistryProtein Kinase CProtein TransportReceptors, Cytoplasmic and NuclearTumor Cells, CulturedConceptsProtein kinase CNucleoplasmic reticulumCalcium signalsNuclear envelopeNuclear protein kinase CNuclear calcium signalsCytosolic protein kinase CGene transcriptionInduces translocationNuclear calcium storesPlasma membraneCytosolic calcium signalsSubnuclear regionsEndoplasmic reticulumSecond messengerKinase CTrisphosphate receptorCell growthReticulumNuclear componentsReticular networkPotential mechanismsCalcium storesRelease of calciumNucleus
1997
Intercellular Calcium Signaling in Liver
Nathanson M, Fallon M, Burgstahler A, Mennone A, Schlosser S, Gonzalez C, Sáez J. Intercellular Calcium Signaling in Liver. Series Of The Centro De Estudios Científicos 1997, 469-481. DOI: 10.1007/978-1-4899-1795-9_27.Peer-Reviewed Original ResearchGap junctionsGap junction expressionIntercellular calcium signalingDiverse cell functionsExcitable cell typesBile secretionIsolated cell systemImportant second messengerJunction expressionCytosolic Ca2Experimental modelHormonal stimulationCell functionPhysiological circumstancesCalcium signalingIntercellular signalingHepatocytesSecond messengerOrgan-level responsesPreliminary evidenceLiverCell typesCai2Inositol 1Signaling
1994
Cellular and subcellular calcium signaling in gastrointestinal epithelium
Nathanson M. Cellular and subcellular calcium signaling in gastrointestinal epithelium. Gastroenterology 1994, 106: 1349-1364. PMID: 8174894, DOI: 10.1016/0016-5085(94)90030-2.Peer-Reviewed Original ResearchConceptsCell typesCritical second messengerEpithelial cell typesEpithelial cellsIndividual epithelial cellsPolarized epitheliumSecond messengerMechanism of Ca2Polarized structureGastrointestinal tractProlonged elevationGastrointestinal epitheliumCell populationsSubcellular calciumSubcellular Ca2Cytosolic Ca2Digestive systemCellsFurther levelCa2EpitheliumSuch signalsSignalingMessengerPancreas