2014
Outcomes in patients undergoing nephrectomy for renal cancer on chronic anticoagulation therapy
Sfakianos J, Hakimi A, Kim P, Zabor E, Mano R, Bernstein M, Karellas M, Russo P. Outcomes in patients undergoing nephrectomy for renal cancer on chronic anticoagulation therapy. European Journal Of Surgical Oncology 2014, 40: 1700-1705. PMID: 24813810, PMCID: PMC4208948, DOI: 10.1016/j.ejso.2014.04.010.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAnticoagulantsAspirinBlood TransfusionFemaleFibrinolytic AgentsHumansIncidenceIntraoperative ComplicationsKidney NeoplasmsLength of StayMaleMiddle AgedNeoplasm StagingNephrectomyPlatelet Aggregation InhibitorsPostoperative ComplicationsRetrospective StudiesRisk FactorsSeverity of Illness IndexTreatment OutcomeUnited StatesConceptsOverall complication rateComplication rateChronic anticoagulationRenal tumorsChronic anticoagulation therapyLength of stayLogistic regression modelsACT patientsAspirin patientsChronic aspirinHigher transfusionAnticoagulation therapyASA scoreAspirin useTransfusion rateAnticoagulation groupSurgical resectionMedian lengthOpen surgeryClinical differencesRenal surgeryGrade 3Renal cancerRetrospective analysisAnticoagulation
2012
Defining the impact of vascular risk factors on erectile function recovery after radical prostatectomy
Teloken P, Nelson C, Karellas M, Stasi J, Eastham J, Scardino P, Mulhall J. Defining the impact of vascular risk factors on erectile function recovery after radical prostatectomy. BJU International 2012, 111: 653-657. PMID: 22758405, DOI: 10.1111/j.1464-410x.2012.11321.x.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAnalysis of VarianceAustraliaDatabases, FactualDiabetes MellitusErectile DysfunctionFollow-Up StudiesHumansHypercholesterolemiaHypertensionMaleMiddle AgedMultivariate AnalysisPenile ErectionProspective StudiesProstatectomyProstatic NeoplasmsRecovery of FunctionRegression AnalysisRisk FactorsSmokingTreatment OutcomeVascular DiseasesConceptsVascular risk factorsErectile function recoveryPreoperative erectile functionRadical prostatectomyFunction recoveryErectile functionRisk factorsPatient factorsSurgical techniquePresence of VRFNerve-sparing statusPostoperative erectile functionNew treatment strategiesProspective databaseEF recoverySTUDY ADDDiabetes mellitusMultivariable analysisCigarette smokingErectile dysfunctionPatient counsellingUnivariate analysisProstate cancerTreatment strategiesPreoperative information
2010
Partial nephrectomy for selected renal cortical tumours of ≥7 cm
Karellas M, O’Brien M, Jang T, Bernstein M, Russo P. Partial nephrectomy for selected renal cortical tumours of ≥7 cm. BJU International 2010, 106: 1484-1487. PMID: 20518765, PMCID: PMC4319322, DOI: 10.1111/j.1464-410x.2010.09405.x.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarcinoma, Renal CellEpidemiologic MethodsHumansKidney CortexKidney NeoplasmsMiddle AgedNephrectomyTreatment OutcomeTumor BurdenConceptsRenal cortical tumorsPartial nephrectomyCortical tumorsRenal unitsLarge tumorsPre-existing renal insufficiencyUse of PNConventional clear cell carcinomaAccepted surgical approachMedian tumor sizeGlomerular filtration rateInstitutional review board approvalClear cell carcinomaEffective tumor controlReview board approvalRenal insufficiencySolitary kidneyMetastatic diseaseMedian ageAppropriate tumorSurgical databaseTumor sizeCell carcinomaSurgical approachTumor control
2008
Advanced‐stage renal cell carcinoma treated by radical nephrectomy and adjacent organ or structure resection
Karellas M, Jang T, Kagiwada M, Kinnaman M, Jarnagin W, Russo P. Advanced‐stage renal cell carcinoma treated by radical nephrectomy and adjacent organ or structure resection. BJU International 2008, 103: 160-164. PMID: 18782305, PMCID: PMC2769168, DOI: 10.1111/j.1464-410x.2008.08025.x.Peer-Reviewed Original ResearchConceptsRenal cell carcinomaRadical nephrectomyAdjacent organsCell carcinomaAdvanced stage renal cell carcinomaAdvanced renal cell carcinomaConventional clear cell carcinomaAdjuvant clinical trialsEvidence of diseaseInstitutional review board approvalPositive surgical marginsSurgical margin statusClear cell carcinomaPathological stage T3Review board approvalPT4 stageMetastatic diseaseMost patientsSurgical resectionSystemic agentsMargin statusSurgical managementSurgical marginsStage T3Clinical trials