2017
Architecture, Function, and Assembly of the Mouse Visual System
Seabrook TA, Burbridge TJ, Crair MC, Huberman AD. Architecture, Function, and Assembly of the Mouse Visual System. Annual Review Of Neuroscience 2017, 40: 499-538. PMID: 28772103, DOI: 10.1146/annurev-neuro-071714-033842.Peer-Reviewed Original ResearchConceptsSpecific cell typesMammalian central nervous systemGenetic perturbationsModel speciesCell typesCausal testingSpeciesVivo labelingBroad scaleVisual system structuresManipulation of neuronsSensory systemsCentral nervous systemVisual circuitryPowerful toolNervous systemLarge cadreHumansMouse visual systemAdditional experimentationPathwayFunctionConvenient sizeAssemblyVisual system
2011
Visual map development depends on the temporal pattern of binocular activity in mice
Zhang J, Ackman JB, Xu HP, Crair MC. Visual map development depends on the temporal pattern of binocular activity in mice. Nature Neuroscience 2011, 15: 298-307. PMID: 22179110, PMCID: PMC3267873, DOI: 10.1038/nn.3007.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsAnimals, NewbornBrain MappingCalciumChannelrhodopsinsCritical Period, PsychologicalFunctional LateralityIn Vitro TechniquesLightLuminescent ProteinsMiceMice, Inbred C57BLMice, TransgenicNeuronal PlasticityPatch-Clamp TechniquesReceptors, NicotinicRetinaRetinal Ganglion CellsSuperior ColliculiTime FactorsVision, BinocularVisual PathwaysConceptsDorsal lateral geniculate nucleusEye-specific segregationSpontaneous retinal wavesLateral geniculate nucleusPrimary visual cortexMouse visual systemBinocular activityRetinal wavesGeniculate nucleusCircuit refinementSuperior colliculusSpecific temporal featuresVisual cortexBursts of activityDefinitive evidenceVisual systemColliculusBinocularityCortexMiceActivityAn Instructive Role for Patterned Spontaneous Retinal Activity in Mouse Visual Map Development
Xu HP, Furman M, Mineur YS, Chen H, King SL, Zenisek D, Zhou ZJ, Butts DA, Tian N, Picciotto MR, Crair MC. An Instructive Role for Patterned Spontaneous Retinal Activity in Mouse Visual Map Development. Neuron 2011, 70: 1115-1127. PMID: 21689598, PMCID: PMC3119851, DOI: 10.1016/j.neuron.2011.04.028.Peer-Reviewed Original ResearchConceptsSpontaneous retinal activityRetinal activityRetinal ganglion cell projectionsEye-specific segregationGanglion cell projectionsSpontaneous retinal wavesActivity-dependent refinementRetinal ganglion cellsMouse visual systemComplex neural circuitsEye of originRetinal wavesGanglion cellsRetinotopic refinementNeuronal activitySpontaneous activityMammalian visual systemAcetylcholine receptorsNeuronal connectivityMammalian brainNeural circuitsOverall activity levelsActivity levelsBrainVisual system