2014
Structural organization and function of mouse photoreceptor ribbon synapses involve the immunoglobulin protein synaptic cell adhesion molecule 1
Ribic A, Liu X, Crair MC, Biederer T. Structural organization and function of mouse photoreceptor ribbon synapses involve the immunoglobulin protein synaptic cell adhesion molecule 1. The Journal Of Comparative Neurology 2014, 522: 900-920. PMID: 23982969, PMCID: PMC3947154, DOI: 10.1002/cne.23452.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol OxidoreductasesAnalysis of VarianceAnimalsAnimals, NewbornCell Adhesion Molecule-1Cell Adhesion MoleculesCo-Repressor ProteinsDNA-Binding ProteinsElectroretinographyFemaleGene Expression Regulation, DevelopmentalImmunoglobulinsMaleMiceMice, Inbred C57BLMice, KnockoutMicroscopy, ImmunoelectronNerve Tissue ProteinsPhosphoproteinsReceptors, Metabotropic GlutamateRetinaRetinal Rod Photoreceptor CellsSynapsesVesicular Glutamate Transport Protein 1ConceptsCell adhesion molecule-1Adhesion molecule-1Ribbon synapsesKO retinasSynaptic cell adhesion molecule 1Molecule-1Mouse photoreceptor ribbon synapsesInner retinal layersPhotoreceptor ribbon synapsesRod visual pathwayEarly postnatal stagesPlexiform layerKO micePhotoreceptor synapsesSynaptic organizationExcitatory synapsesQuantitative ultrastructural analysisRetinal layersKnockout miceOuter nuclearVisual pathwaySynapse developmentElectroretinogram recordingsPostnatal stagesAdhesion molecules
2002
Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth.
Wang SW, Mu X, Bowers WJ, Kim DS, Plas DJ, Crair MC, Federoff HJ, Gan L, Klein WH. Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development 2002, 129: 467-77. PMID: 11807038, DOI: 10.1242/dev.129.2.467.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxonsCell DifferentiationCulture TechniquesDNA-Binding ProteinsFemaleGene TargetingHumansMaleMiceMice, KnockoutMicroscopy, FluorescenceNeuritesRetinaRetinal Ganglion CellsTranscription Factor Brn-3Transcription Factor Brn-3ATranscription Factor Brn-3BTranscription Factor Brn-3CTranscription FactorsConceptsDouble knockout miceGanglion cell differentiationRetinal ganglion cell differentiationRetinal ganglion cellsOptic chiasmKnockout miceGanglion cellsMost retinal ganglion cellsRetinal ganglion cell axonsRetinal ganglion cell developmentGanglion cell axonsAxon outgrowthGanglion cell developmentCell differentiationDorsal rootsProjection neuronsTrigeminal ganglionCell axonsRetinal explantsPOU domain transcription factorBrn3bBrn3cMiceChiasmInner ear
2001
Barrel Cortex Critical Period Plasticity Is Independent of Changes in NMDA Receptor Subunit Composition
Lu H, Gonzalez E, Crair M. Barrel Cortex Critical Period Plasticity Is Independent of Changes in NMDA Receptor Subunit Composition. Neuron 2001, 32: 619-634. PMID: 11719203, DOI: 10.1016/s0896-6273(01)00501-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrain MappingCritical Period, PsychologicalExcitatory Amino Acid AntagonistsExcitatory Postsynaptic PotentialsGene Expression Regulation, DevelopmentalLong-Term PotentiationMiceMice, Inbred C57BLMice, KnockoutNeuronal PlasticityPiperidinesQuinoxalinesReceptors, AMPAReceptors, N-Methyl-D-AspartateSomatosensory CortexSynapsesThalamusConceptsNMDA receptor subunit compositionReceptor subunit compositionSubunit compositionMouse somatosensory barrel cortexCritical periodNR2A knockout miceCritical period plasticitySomatosensory barrel cortexNMDAR subunit compositionCurrent kineticsAfferent innervationBarrel cortexNR2B subunitKnockout miceSynaptic plasticityNR2A subunitPlasticity windowSubunits