2017
Reciprocal Connections Between Cortex and Thalamus Contribute to Retinal Axon Targeting to Dorsal Lateral Geniculate Nucleus
Diao Y, Cui L, Chen Y, Burbridge TJ, Han W, Wirth B, Sestan N, Crair MC, Zhang J. Reciprocal Connections Between Cortex and Thalamus Contribute to Retinal Axon Targeting to Dorsal Lateral Geniculate Nucleus. Cerebral Cortex 2017, 28: 1168-1182. PMID: 28334242, PMCID: PMC6059179, DOI: 10.1093/cercor/bhx028.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsAnimals, NewbornAxonsCalciumCholera ToxinDNA-Binding ProteinsEmbryo, MammalianExcitatory Amino Acid AgonistsFeeding BehaviorGene Expression Regulation, DevelopmentalGeniculate BodiesGreen Fluorescent ProteinsHomeodomain ProteinsMiceMice, TransgenicNerve Tissue ProteinsRetinaSerine-Arginine Splicing FactorsSuperior ColliculiTranscription FactorsVisual CortexVisual PathwaysConceptsDorsal lateral geniculate nucleusLateral geniculate nucleusVentral lateral geniculate nucleusGeniculate nucleusRetinal projectionsReciprocal connectionsSuperior colliculusConditional knockoutVivo electrophysiology experimentsAbnormal retinal projectionsPrimary visual cortexDLGN neuronsCorticothalamic inputsControl miceThalamocortical tractV1 lesionsThalamus contributeRetinal innervationThalamocortical projectionsCKO miceMouse modelRetinal inputVisual cortexVisual circuitsAxon targeting
2012
Role of adenylate cyclase 1 in retinofugal map development
Dhande OS, Bhatt S, Anishchenko A, Elstrott J, Iwasato T, Swindell EC, Xu H, Jamrich M, Itohara S, Feller MB, Crair MC. Role of adenylate cyclase 1 in retinofugal map development. The Journal Of Comparative Neurology 2012, 520: 1562-1583. PMID: 22102330, PMCID: PMC3563095, DOI: 10.1002/cne.23000.Peer-Reviewed Original ResearchConceptsLateral geniculate nucleusDorsal lateral geniculate nucleusAdenylate cyclase 1Superior colliculusRetinal wavesRetinal ganglion cell projectionsEye-specific segregationGanglion cell projectionsSpontaneous retinal wavesSecond postnatal weekActivity-dependent processesCyclase 1Production of cAMPRGC axonsGeniculate nucleusPostnatal weekMammalian visual systemDevelopment of retinotopySomatotopic mapMutant miceSensory peripheryMiceConditional deletionTermination zonesDependent manner
2011
Visual map development depends on the temporal pattern of binocular activity in mice
Zhang J, Ackman JB, Xu HP, Crair MC. Visual map development depends on the temporal pattern of binocular activity in mice. Nature Neuroscience 2011, 15: 298-307. PMID: 22179110, PMCID: PMC3267873, DOI: 10.1038/nn.3007.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsAnimals, NewbornBrain MappingCalciumChannelrhodopsinsCritical Period, PsychologicalFunctional LateralityIn Vitro TechniquesLightLuminescent ProteinsMiceMice, Inbred C57BLMice, TransgenicNeuronal PlasticityPatch-Clamp TechniquesReceptors, NicotinicRetinaRetinal Ganglion CellsSuperior ColliculiTime FactorsVision, BinocularVisual PathwaysConceptsDorsal lateral geniculate nucleusEye-specific segregationSpontaneous retinal wavesLateral geniculate nucleusPrimary visual cortexMouse visual systemBinocular activityRetinal wavesGeniculate nucleusCircuit refinementSuperior colliculusSpecific temporal featuresVisual cortexBursts of activityDefinitive evidenceVisual systemColliculusBinocularityCortexMiceActivityDevelopment of Single Retinofugal Axon Arbors in Normal and β2 Knock-Out Mice
Dhande OS, Hua EW, Guh E, Yeh J, Bhatt S, Zhang Y, Ruthazer ES, Feller MB, Crair MC. Development of Single Retinofugal Axon Arbors in Normal and β2 Knock-Out Mice. Journal Of Neuroscience 2011, 31: 3384-3399. PMID: 21368050, PMCID: PMC3060716, DOI: 10.1523/jneurosci.4899-10.2011.Peer-Reviewed Original ResearchConceptsDorsal lateral geniculate nucleusRetinal ganglion cellsSuperior colliculusAxon arborsRetinotopic refinementEye-specific segregationReceptor mutant miceLateral geniculate nucleusActivity-dependent mechanismsNormal developmentWT miceRGC axonsRetinal wavesGanglion cellsGeniculate nucleusMutant miceRole of activityMiceSpecific cuesArborsSparse branchesSame ageLabeling techniqueMaturationDevelopmental period