2007
Characterization of Early Stages of Human B Cell Development by Gene Expression Profiling
Hystad ME, Myklebust JH, Bø TH, Sivertsen EA, Rian E, Forfang L, Munthe E, Rosenwald A, Chiorazzi M, Jonassen I, Staudt LM, Smeland EB. Characterization of Early Stages of Human B Cell Development by Gene Expression Profiling. The Journal Of Immunology 2007, 179: 3662-3671. PMID: 17785802, DOI: 10.4049/jimmunol.179.6.3662.Peer-Reviewed Original ResearchConceptsHuman B cell developmentB cell developmentGene expression profilingCell developmentTranscription factorsExpression profilingHemopoietic stem cellsLineage-associated transcription factorsInteresting expression patternsStem cellsMyeloid-associated genesExpression of genesAdult bone marrowFunctional assignmentImmature B cellsKey genesCDNA microarrayGene setsExpression patternsVDJ recombinationUnknown roleB-lymphoid cellsGenesB cellsRNA amplification
2006
Characterization of Early Human B Cell Development by Gene Expression Profiling.
Hystad M, Bo T, Rian E, Myklebust J, Sivertsen E, Forfang L, Chiorazzi M, Rosenwald A, Jonassen I, Staudt L, Smeland E. Characterization of Early Human B Cell Development by Gene Expression Profiling. Blood 2006, 108: 1352. DOI: 10.1182/blood.v108.11.1352.1352.Peer-Reviewed Original ResearchB cell developmentHematopoietic stem cellsHuman B cell developmentGene expression profilingGene expressionFluorescence-activated cell sortingHigh expression levelsImmature B cellsGene OntologyExpression profilingCell developmentB cell lineage commitmentCell populationsTranscription factor E2AEarly B cell developmentExpression levelsExpression of genesProgenitor B cellsPro-B CellsSubsequent fluorescence-activated cell sortingAdult human bone marrowB lineage cellsGene pairsRecombination genesLineage commitment