2012
Splenic conservation: Variation between pediatric and adult trauma centers
Lippert SJ, Hartin CW, Ozgediz DE, Glick PL, Caty MG, Flynn WJ, Bass KD. Splenic conservation: Variation between pediatric and adult trauma centers. Journal Of Surgical Research 2012, 182: 17-20. PMID: 22939554, DOI: 10.1016/j.jss.2012.07.036.Peer-Reviewed Original ResearchConceptsAdult level I trauma centerPediatric Level I Trauma CenterHigher Injury Severity ScoreLevel I trauma centerI trauma centerInjury Severity ScoreSplenic injuryLocation of presentationTrauma centerNonoperative managementSeverity scoreAdult trauma centersBlunt splenic injuryOnly independent factorLogistic multivariate analysisStudent's t-testHospital coursePatients 14Older patientsLonger LOSNonoperative approachRetrospective reviewTrauma registryAdolescent patientsStable children
2003
Beneficial effects of intraluminal nitroglycerin in intestinal ischemia-reperfusion injury in rats1 1This study was supported by NIH grant HL22273, the R.J. Stransky Foundation, and the Women and Children’s Health Research Foundation of the Children’s Hospital of Buffalo.
Khanna A, Rossman J, Caty MG, Fung H. Beneficial effects of intraluminal nitroglycerin in intestinal ischemia-reperfusion injury in rats1 1This study was supported by NIH grant HL22273, the R.J. Stransky Foundation, and the Women and Children’s Health Research Foundation of the Children’s Hospital of Buffalo. Journal Of Surgical Research 2003, 114: 15-24. PMID: 13678693, DOI: 10.1016/s0022-4804(03)00329-9.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, TopicalAnimalsBileHemodynamicsIntestinal DiseasesIntestinal MucosaIntestinesMaleModels, AnimalNeutrophil ActivationNeutrophil InfiltrationNitric OxideNitroglycerinPermeabilityPlatelet Activating FactorRatsRats, Sprague-DawleyReactive Oxygen SpeciesReperfusion InjuryVasodilator AgentsConceptsIntestinal ischemia-reperfusion injuryIschemia-reperfusion injuryHealth Research FoundationBile flowMean arterial pressureAdministration of nitroglycerinIntestinal barrier functionIntestinal ischemiaMucosal injurySystemic hemodynamicsArterial pressureHypotensive effectIntestinal pathologyChildren's HospitalIntestinal IRIntestinal permeabilityRat modelSustained decreaseExperimental diseaseSystemic effectsNitroglycerinBeneficial effectsPhysiologic functionDifferent dosesBarrier function
2001
Intestinal and Hemodynamic Impairment Following Mesenteric Ischemia/Reperfusion
Khanna A, Rossman J, Fung H, Caty M. Intestinal and Hemodynamic Impairment Following Mesenteric Ischemia/Reperfusion. Journal Of Surgical Research 2001, 99: 114-119. PMID: 11421612, DOI: 10.1006/jsre.2001.6103.Peer-Reviewed Original ResearchConceptsMean arterial pressureR injuryRat modelHeart rateAnimal modelsMesenteric ischemia/reperfusionBarrier functionReperfusion injury resultsSuperior mesenteric arteryIschemia/reperfusionNormal barrier functionArterial pressureHemodynamic effectsIntestinal damageMesenteric occlusionHemodynamic measurementsMesenteric arterySmall bowelFemoral arterySustained fallIntestinal permeabilityInjury resultsAnesthetized ratsIntestinal impairmentHistological disruption