2017
Protein Intake in Chronic Kidney Disease
Sarav M, McKnight C, Newberry C. Protein Intake in Chronic Kidney Disease. Current Nutrition Reports 2017, 6: 257-260. DOI: 10.1007/s13668-017-0213-y.Peer-Reviewed Original ResearchChronic kidney diseasePoor nutritional statusKidney diseaseProtein intakeKeto-analogues of essential amino acidsNutritional statusChronic kidney disease patientsProgression of chronic kidney diseaseProtein-energy wastingLow protein intakeRecent FindingsRecent studiesSummaryIn summaryIndividual patient needsKidney functionComplex nutritional requirementsFindingsRecent studiesReviewThe purposePatientsPracticing nephrologistsAssociated with increasesAcute illnessHealthy adultsKeto analoguesIntakeDisease
2014
Cinacalcet hydrochloride for the treatment of hyperparathyroidism
Sarav M, Sprague S. Cinacalcet hydrochloride for the treatment of hyperparathyroidism. Expert Opinion On Orphan Drugs 2014, 2: 851-863. DOI: 10.1517/21678707.2014.940311.Peer-Reviewed Original ResearchSecondary hyperparathyroidismTreatment of secondary hyperparathyroidismComplication of chronic kidney diseaseSevere primary hyperparathyroidismParathyroid hormone excessTreatment of hyperparathyroidismCalcium-sensing receptorChronic kidney diseasePrimary hyperparathyroidismCalcimimetic agentHormone excessDevelopment of agentsSafety profileClinical efficacyG protein-coupled receptorsClinical indicationsCalcium metabolismDialysis patientsHyperparathyroidismKidney diseaseCaSRCinacalcetCinacalcet hydrochlorideCalcimimeticsReceptors
2010
Chronic kidney disease induced in mice by reversible unilateral ureteral obstruction is dependent on genetic background
Puri T, Shakaib M, Chang A, Mathew L, Olayinka O, Minto A, Sarav M, Hack B, Quigg R. Chronic kidney disease induced in mice by reversible unilateral ureteral obstruction is dependent on genetic background. American Journal Of Physiology. Renal Physiology 2010, 298: f1024-f1032. PMID: 20089676, PMCID: PMC2853313, DOI: 10.1152/ajprenal.00384.2009.Peer-Reviewed Original ResearchConceptsReversible unilateral ureteral obstructionChronic kidney diseaseUnilateral ureteral obstructionDevelopment of chronic kidney diseaseUreteral obstructionBlood urea nitrogenC57BL/6 miceResistant to chronic kidney diseaseBALB/c miceKidney diseaseModel of chronic kidney diseaseDays of ureteral obstructionRelease of ureteral obstructionModel of renal fibrosisBackground Chronic kidney diseaseProliferative cellular responseResponse to injuryRenal injuryRenal fibrosisRenal architectureObstructionUrea nitrogenMiceC57BL/6Injury