2008
Influence of Sex on Sleep Regulatory Mechanisms
Paul KN, Turek FW, Kryger MH. Influence of Sex on Sleep Regulatory Mechanisms. Journal Of Women's Health 2008, 17: 1201-1208. PMID: 18710368, DOI: 10.1089/jwh.2008.0841.Peer-Reviewed Original ResearchConceptsSleep regulatory mechanismsRodent studiesSleep-wake disordersReproductive hormonesExtended wakefulnessHomeostatic sleep regulatory mechanismsSleep consolidationSleep-wake amountsActivational influencesBiological sexRapid eye movement (REM) sleepSleep-wake architectureSleep amountSleep-wake cycleEffects of sexFemale reproductive hormonesSleepEye movement sleepSleep-wake statesInfluence of sexSleep disordersSleep statesPositive impactWakefulnessNeonatal exposure
2005
Cytokines and normal sleep
Kapsimalis F, Richardson G, Opp MR, Kryger M. Cytokines and normal sleep. Current Opinion In Pulmonary Medicine 2005, 11: 481-484. PMID: 16217172, DOI: 10.1097/01.mcp.0000183062.98665.6b.Peer-Reviewed Original ResearchConceptsNon-rapid eye movement sleepEye movement sleepNeurohormonal systemsMovement sleepSpontaneous non-rapid eye movement sleepMultiple biologic actionsHypothalamic preoptic areaReceptor-mediated effectsTumor necrosis factorNitric oxide synthesisEffects of cytokinesDirect receptor-mediated effectsImmune system responseMechanism of actionSleep-wake regulationSite of actionAdrenal axisBasal forebrainPreoptic areaNecrosis factorInterleukin-1Adrenal axesNormal sleepCytokinesOxide synthesis
1987
Perfluorochemical Artificial Blood as a Volume Expander in Hypoxemic Respiratory Failure in Dogs
Light R, Perez-Padilla R, Kryger M. Perfluorochemical Artificial Blood as a Volume Expander in Hypoxemic Respiratory Failure in Dogs. CHEST Journal 1987, 91: 444-449. PMID: 3816321, DOI: 10.1378/chest.91.3.444.Peer-Reviewed Original ResearchConceptsAdult respiratory distress syndromeArteriovenous O2 content differenceHypoxemic respiratory failureArterial O2 contentO2 content differenceVolume expandersRespiratory failureIntrapulmonary shuntPFC groupFluosol-DARespiratory distress syndromeSystemic vascular pressuresArterial O2 tensionEffective volume expanderTissue O2 deliveryOriginal disorderDistress syndromeCentral hemodynamicsPulmonary edemaCardiac outputContent differenceBlood productsVascular pressuresO2 deliveryPerfluorochemical artificial blood
1972
Gas diffusion across collateral channels.
Hogg W, Brunton J, Kryger M, Brown R, Macklem P. Gas diffusion across collateral channels. Journal Of Applied Physiology 1972, 33: 568-575. PMID: 4635918, DOI: 10.1152/jappl.1972.33.5.568.Peer-Reviewed Original Research