2008
Association of Sleep Apnea Severity and Obesity with Insulin Resistance, C-Reactive Protein, and Leptin Levels in Male Patients with Obstructive Sleep Apnea
Kapsimalis F, Varouchakis G, Manousaki A, Daskas S, Nikita D, Kryger M, Gourgoulianis K. Association of Sleep Apnea Severity and Obesity with Insulin Resistance, C-Reactive Protein, and Leptin Levels in Male Patients with Obstructive Sleep Apnea. Lung 2008, 186: 209-217. PMID: 18365276, DOI: 10.1007/s00408-008-9082-x.Peer-Reviewed Original ResearchConceptsObstructive sleep apnea syndromeSleep apnea severityObstructive sleep apneaNon-OSA groupBody mass indexModerate OSAS groupCRP levelsInsulin resistanceApnea severityOSAS groupMale patientsLeptin levelsSleep apneaSevere obstructive sleep apnea syndromeHomeostasis model assessment methodSevere sleep apneaSevere OSAS groupSleep apnea syndromeC-reactive proteinTotal sleep timeNocturnal hypoxemiaApnea syndromeModel assessment methodHip ratioMass index
2002
Gender and Obstructive Sleep Apnea Syndrome, Part 2: Mechanisms
Kapsimalis F, Kryger MH. Gender and Obstructive Sleep Apnea Syndrome, Part 2: Mechanisms. Sleep 2002, 25: 497-504. PMID: 12150315, DOI: 10.1093/sleep/25.5.497.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsObstructive sleep apnea syndromeSleep apnea syndromeApnea syndromeUpper airway muscle functionHormone replacement therapyUpper airway anatomySleep breathing disordersControl of ventilationOSAS prevalenceBreathing disordersReplacement therapySex hormonesCommon disorderFemale genderMuscle functionEpidemiologic studiesAdipose tissueSyndromeDisordersAdult malesGenderRiskFemalesPercentObesity