2022
Catechol-O-Methyltransferase Effects on Smoking: a Review and Proof of Concept of Sex-Sensitive Effects
DeVito E, Sofuoglu M. Catechol-O-Methyltransferase Effects on Smoking: a Review and Proof of Concept of Sex-Sensitive Effects. Current Behavioral Neuroscience Reports 2022, 9: 113-123. PMID: 36644316, PMCID: PMC9838826, DOI: 10.1007/s40473-022-00251-2.Peer-Reviewed Original ResearchSmoking behaviorPreliminary dataHuman laboratory studiesCigarette smoking behaviorShort-term abstinenceNicotine administrationSmoking cessationTreatment optionsWithdrawal symptomsCessation outcomesPharmacogenetic effectsOvernight abstinenceMet carriersSmoking urgesActivity genotypeReviewThis articleSymptomsCOMT geneSex differencesAbstinenceFunctional variantsSmokingCigarettesAdministrationIndividuals
2001
Depressive symptoms modulate the subjective and physiological response to cocaine in humans
Sofuoglu M, Brown S, Babb D, Hatsukami D. Depressive symptoms modulate the subjective and physiological response to cocaine in humans. Drug And Alcohol Dependence 2001, 63: 131-137. PMID: 11376917, DOI: 10.1016/s0376-8716(00)00199-x.Peer-Reviewed Original ResearchConceptsDepressive symptomsCocaine responseBeck Depression Inventory scoresHigher BDI groupLower BDI scoresDepression Inventory scoresSubclinical depressive symptomsBody weight differencesInpatient studyMajor depressionBDI scoresCocaine use behaviorBDI groupInventory scoresSymptomsCocaineCocaine usersPhysiological responsesGroup differencesEnhanced responseSubjective responsesWeight differencesScoresUse behaviorsResponse
1998
Effects of cotinine on cigarette self-administration
Hatsukami D, Lexau B, Nelson D, Pentel P, Sofuoglu M, Goldman A. Effects of cotinine on cigarette self-administration. Psychopharmacology 1998, 138: 184-189. PMID: 9718288, DOI: 10.1007/s002130050661.Peer-Reviewed Original ResearchConceptsDoses of cotinineWithdrawal symptomsCigarette withdrawal symptomsEffects of cotinineNicotine serum levelsSelective modulatory effectNicotine withdrawal symptomsNumber of cigarettesEffects of nicotineMetabolite of nicotineSubjective responsesNicotine patchSerum levelsCigarette smokingNicotine intakeModulatory effectsCarbon monoxide levelsCotinineRandomized orderPlaceboBeneficial effectsCigarettesOutcome variablesDosesSymptoms