2024
The combination of donepezil and cognitive training for improving treatment outcomes for alcohol use disorder: Design of a randomized controlled trial
Yoon G, Sofuoglu M, Petrakis I, Pittman B, Bell M. The combination of donepezil and cognitive training for improving treatment outcomes for alcohol use disorder: Design of a randomized controlled trial. Contemporary Clinical Trials 2024, 145: 107657. PMID: 39111388, PMCID: PMC11423257, DOI: 10.1016/j.cct.2024.107657.Peer-Reviewed Original ResearchCognitive remediation therapyAlcohol use disorderAlcohol use disorder treatment outcomesNeurocognitive functionCombination of donepezilRemediation therapyUse disorderTreatment outcomesDevelopment of alcohol use disordersReduce heavy drinking daysHeavy drinking daysGlobal neurocognitive functioningImprove neurocognitive functionEnhanced neurocognitive functionImprove cognitive functionRandomized controlled trialsReduce alcohol consumptionNeurobiological evidenceDrinking daysNeurocognitive function scoresCognitive trainingVA Connecticut Healthcare SystemCognitive functionImprove treatment outcomesCognitive impairment
2023
On the Edges: The Ethics of Human Studies with Psychedelic Substances
da Costa S, Sofuoglu M. On the Edges: The Ethics of Human Studies with Psychedelic Substances. 2023, 153-171. DOI: 10.1007/978-3-031-14339-7_9.Peer-Reviewed Original ResearchClinical benefitLife-threatening conditionNovel pharmacological agentsAlcohol use disorderClinical studiesDepressive symptomsHuman studiesPharmacological agentsUse disordersMedical supervisionClassical psychedelicsTherapeutic potentialClinical researchPsychoactive effectsPsychedelic substancesControlled Substances ActHuman researchAccepted medical useConsistent evidenceDisordersPsychedelicsSubstances ActSchedule IMedical useRecreational use
2022
Pilot examination of stress, heart rate variability, and alcohol craving and use among female veterans
Holzhauer CG, Epstein EE, Bickar L, Ellis RA, Pole N, Sofuoglu M, Smelson DA, Mattocks K. Pilot examination of stress, heart rate variability, and alcohol craving and use among female veterans. Frontiers In Psychiatry 2022, 13: 886801. PMID: 36159929, PMCID: PMC9500469, DOI: 10.3389/fpsyt.2022.886801.Peer-Reviewed Original ResearchHeart rate variabilityAlcohol use disorderAlcohol cravingAlcohol misuseFemale veteransRate variabilityStudy periodSelf-reported alcohol cravingPilot dataAssociation of stressSelf-report questionnairesUse disordersVeteran populationWomen veteransDaily drinksDaily assessmentAlcohol useDaily cravingPilot studyOverall alcoholCravingSuccessive differencesPotential roleWomenPilot examination
2019
Pharmacotherapies for PTSD and Substance Use Disorders
Kachadourian L, Jensen K, Sofuoglu M, Petrakis I. Pharmacotherapies for PTSD and Substance Use Disorders. 2019, 239-259. DOI: 10.4324/9781315442648-13.ChaptersOpioid use disorderAlcohol use disorderPosttraumatic stress disorderUse disordersPTSD/SUDPharmacological treatmentComorbid posttraumatic stress disorderUse of pharmacotherapySubstance use disordersEffectiveness of foodIntramuscular naltrexoneLabel medicationsEpidemiological studiesMedication developmentDrug AdministrationPharmacotherapyStress disorderAvailable evidenceDisordersNew targetsNaltrexoneTreatmentBiological mechanismsSpecific substancesSUD
2017
Inhalation of Alcohol Vapor: Measurement and Implications
MacLean RR, Valentine GW, Jatlow PI, Sofuoglu M. Inhalation of Alcohol Vapor: Measurement and Implications. Alcohol Clinical And Experimental Research 2017, 41: 238-250. PMID: 28054395, PMCID: PMC6143144, DOI: 10.1111/acer.13291.Peer-Reviewed Original ResearchConceptsAlcohol inhalationAlcohol consumptionAcute alcohol exposureElevated blood alcohol concentrationsRoute of administrationOral alcohol consumptionFirst-pass metabolismAlcohol use disorderPublic health concernMeasurement of biomarkersBlood alcohol concentrationRisk of addictionPharmacodynamic profileAlcohol exposureArterial circulationOccupational exposureMeasurable biomarkersPharmacological effectsUse disordersInhalationE-cigarettesHealth concernSubjective effectsRisk of problemsGoogle Scholar