2016
Society of Surgical Oncology–American Society for Radiation Oncology–American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma In Situ
Morrow M, Van Zee KJ, Solin LJ, Houssami N, Chavez-MacGregor M, Harris JR, Horton J, Hwang S, Johnson PL, Marinovich ML, Schnitt SJ, Wapnir I, Moran MS. Society of Surgical Oncology–American Society for Radiation Oncology–American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma In Situ. Journal Of Clinical Oncology 2016, 34: 4040-4046. PMID: 27528719, PMCID: PMC5477830, DOI: 10.1200/jco.2016.68.3573.Peer-Reviewed Original ResearchConceptsIpsilateral breast tumor recurrenceWhole breast irradiationRisk of IBTRNegative marginsDuctal carcinomaRate of IBTRSurgical Oncology–American SocietyMargin widthMultidisciplinary consensus panelBreast tumor recurrenceBreast conserving surgeryBreast-conserving surgeryNegative margin widthOptimal negative margin widthRe-excision ratesHealth care costsFurther surgeryPositive marginsBreast irradiationConsensus guidelinesCosmetic outcomeTumor recurrenceClear marginsConsensus panelBackground Controversy
2014
Should triple-negative breast cancer (TNBC) subtype affect local-regional therapy decision making?
Moran MS. Should triple-negative breast cancer (TNBC) subtype affect local-regional therapy decision making? American Society Of Clinical Oncology Educational Book 2014, e32-6. PMID: 24857120, DOI: 10.14694/edbook_am.2014.34.e32.Peer-Reviewed Original ResearchConceptsTriple-negative breast cancerLocal-regional relapseBreast cancer therapySporadic triple-negative breast cancerBreast cancerEarly-stage triple-negative breast cancerYounger ageAggressive biologic characteristicsBreast conservation approachHER2-positive subgroupContralateral breast cancerWhole breast irradiationDefinitive treatment strategyNegative breast cancer subtypeHypothesis-generating dataPartial breast irradiationBreast cancer subtypesBRCA1 mutation carriersSystemic chemotherapyAdvanced diseaseRandomized trialsGuideline recommendationsLuminal tumorsBreast irradiationTNBC subtypes
2011
ACR Appropriateness Criteria® Conservative surgery and Radiation – Stage I and II Breast Carcinoma
Bellon JR, Harris EE, Arthur DW, Bailey L, Carey L, Goyal S, Halyard MY, Horst KC, Moran MS, MacDonald SM, Haffty BG. ACR Appropriateness Criteria® Conservative surgery and Radiation – Stage I and II Breast Carcinoma. The Breast Journal 2011, 17: 448-455. PMID: 21790842, DOI: 10.1111/j.1524-4741.2011.01132.x.Peer-Reviewed Original ResearchConceptsRadiation therapySide effectsEarly-stage breast cancerLong-term side effectsAdjuvant radiation therapyAcute side effectsACR Appropriateness CriteriaWhole breast irradiationRisk of recurrenceAtherosclerotic heart diseasePartial breast irradiationMajority of womenConservative surgerySurvival benefitAppropriate patientsBreast conservationRandomized studyAppropriateness CriteriaHeart diseaseBreast carcinomaBreast cancerTherapyShort treatmentEffective alternativeTreatment
2010
Racial Disparities in Treatment Outcomes for African American Women with Ductal Carcinoma In Situ Receiving Whole Breast Irradiation following Breast Conserving Surgery
Nelson C, Goyal S, Moran M, Motwani S, Haffty B. Racial Disparities in Treatment Outcomes for African American Women with Ductal Carcinoma In Situ Receiving Whole Breast Irradiation following Breast Conserving Surgery. International Journal Of Radiation Oncology • Biology • Physics 2010, 78: s222. DOI: 10.1016/j.ijrobp.2010.07.533.Peer-Reviewed Original Research
2009
Evaluation of Single Nucleotide Polymorphisms (SNP) in the P53 Binding Protein Gene (TP53BP1), in Breast Cancer Patients Treated with Breast Conserving Surgery and Whole-breast Irradiation (BCS+RT)
Haffty B, Goyal S, Green C, Schiff D, Yang Q, Moran M, Kulkarni D, Ganesan S, Hirshfield K. Evaluation of Single Nucleotide Polymorphisms (SNP) in the P53 Binding Protein Gene (TP53BP1), in Breast Cancer Patients Treated with Breast Conserving Surgery and Whole-breast Irradiation (BCS+RT). International Journal Of Radiation Oncology • Biology • Physics 2009, 75: s6. DOI: 10.1016/j.ijrobp.2009.07.040.Peer-Reviewed Original Research