2021
The Incidence and Cumulative Risk of Major Surgery in Older Persons in the United States
Becher RD, Vander Wyk B, Leo-Summers L, Desai MM, Gill TM. The Incidence and Cumulative Risk of Major Surgery in Older Persons in the United States. Annals Of Surgery 2021, 277: 87-92. PMID: 34261884, PMCID: PMC8758792, DOI: 10.1097/sla.0000000000005077.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overDementiaHumansIncidenceLongitudinal StudiesMedicareProspective StudiesUnited StatesConceptsMajor surgeryOlder personsCumulative riskNational HealthCommunity-living older personsHigh-quality surgical careNon-frail groupPopulation-based incidenceService Medicare beneficiariesMedicaid Services dataCumulative risk estimatesProspective longitudinal studyUnited States agesAging Trends StudyGeriatric characteristicsRepresentative incidenceFrail groupAdjusted incidenceGeriatric populationProbable dementiaSurgical carePersons 85Medicare beneficiariesSurgeryVulnerable subgroups
2019
Factors Associated with Dissatisfaction in Medical Care Quality among Older Medicare Beneficiaries Suffering from Mental Illness
Travers JL, Le C, Desai MM, Merrill JA. Factors Associated with Dissatisfaction in Medical Care Quality among Older Medicare Beneficiaries Suffering from Mental Illness. Journal Of Aging & Social Policy 2019, 33: 51-66. PMID: 31266436, DOI: 10.1080/08959420.2019.1628624.Peer-Reviewed Original ResearchConceptsMedical care qualityMental health disordersOlder adultsCare qualityHealth disordersOlder Medicare beneficiariesPrimary care providersPrimary care practicesUS older adultsMedicaid Services dataMental health needsCare providersMedicare beneficiariesSatisfactory careCare practicesMental illnessHealth needsEthnic differencesAdultsDisordersService dataIllnessFactorsCareEligibility for Local Therapies in Adolescents and Adults with Cutaneous Leishmaniasis from Southwestern Colombia: A Cross-Sectional Study.
Uribe-Restrepo AF, Prieto MD, Cossio A, Desai M, Castro M. Eligibility for Local Therapies in Adolescents and Adults with Cutaneous Leishmaniasis from Southwestern Colombia: A Cross-Sectional Study. American Journal Of Tropical Medicine And Hygiene 2019, 100: 306-310. PMID: 30628567, PMCID: PMC6367628, DOI: 10.4269/ajtmh.18-0643.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAntimonyAntiprotozoal AgentsChildColombiaCross-Sectional StudiesCryotherapyFemaleHumansHyperthermia, InducedLeishmania braziliensisLeishmania guyanensisLeishmaniasis, CutaneousMaleMiddle AgedParomomycinPentamidinePractice Guidelines as TopicSeverity of Illness IndexConceptsLocal therapyPan American Health OrganizationCutaneous leishmaniasisWorld Health OrganizationIndividualized risk-benefit assessmentCases of CLHealth OrganizationProportion of patientsLarge referral centerRisk-benefit assessmentDifferent treatment guidelinesMaximum lesion sizeReferral centerTreatment guidelinesSystemic drugsWHO criteriaCL patientsSectional studyLeishmania VianniaHigh burdenSevere casesLower riskLesion sizePatientsMild presentation
2016
Vena Caval Filter Utilization and Outcomes in Pulmonary Embolism Medicare Hospitalizations From 1999 to 2010
Bikdeli B, Wang Y, Minges KE, Desai NR, Kim N, Desai MM, Spertus JA, Masoudi FA, Nallamothu BK, Goldhaber SZ, Krumholz HM. Vena Caval Filter Utilization and Outcomes in Pulmonary Embolism Medicare Hospitalizations From 1999 to 2010. Journal Of The American College Of Cardiology 2016, 67: 1027-1035. PMID: 26940921, PMCID: PMC5322943, DOI: 10.1016/j.jacc.2015.12.028.Peer-Reviewed Original Research
2015
The Value of Continuous ST-Segment Monitoring in the Emergency Department
Bovino LR, Funk M, Pelter MM, Desai MM, Jefferson V, Andrews LK, Forte K. The Value of Continuous ST-Segment Monitoring in the Emergency Department. Advanced Emergency Nursing Journal 2015, 37: 290-300. PMID: 26509726, PMCID: PMC4644066, DOI: 10.1097/tme.0000000000000080.Peer-Reviewed Original ResearchConceptsContinuous ST-segment monitoringAcute coronary syndromeST-segment monitoringEmergency departmentAdverse eventsDiagnostic accuracyRisk-stratified analysisLikelihood ratioSingle emergency departmentHigh-risk participantsCoronary syndromeElectrocardiographic monitoringMedian timeTroponin (HEART) scoreMyocardial ischemiaRisk factorsHigh riskDiagnostic benefitIschemiaIntervention phaseDiagnosisBedside monitorsInfarctionPatientsSymptomsNational Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010)
Minges KE, Bikdeli B, Wang Y, Kim N, Curtis JP, Desai MM, Krumholz HM. National Trends in Pulmonary Embolism Hospitalization Rates and Outcomes for Adults Aged ≥65 Years in the United States (1999 to 2010). The American Journal Of Cardiology 2015, 116: 1436-1442. PMID: 26409636, PMCID: PMC4841688, DOI: 10.1016/j.amjcard.2015.07.068.Peer-Reviewed Original ResearchConceptsHospitalization ratesMortality rateReadmission ratesBlack patientsPrincipal discharge diagnosis codeOlder adultsCause readmission rateHospital mortality rateProportion of patientsRetrospective cohort studyDischarge diagnosis codesSkilled nursing facilitiesNational trendsSignificant racial differencesHigh rateHome health careHospital stayAdults AgedCohort studyMore patientsTherapeutic advancesDiagnosis codesMedicare feeNursing facilitiesSignificant burdenObesity not associated with severity among hospitalized adults with seasonal influenza virus infection
Braun ES, Crawford FW, Desai MM, Meek J, Kirley PD, Miller L, Anderson EJ, Oni O, Ryan P, Lynfield R, Bargsten M, Bennett NM, Lung KL, Thomas A, Mermel E, Lindegren ML, Schaffner W, Price A, Chaves SS. Obesity not associated with severity among hospitalized adults with seasonal influenza virus infection. Infection 2015, 43: 569-575. PMID: 26148927, DOI: 10.1007/s15010-015-0802-x.Peer-Reviewed Original ResearchConceptsSeasonal influenza virus infectionMultivariate logistic regression modelSeasonal influenza severityLaboratory-confirmed influenzaRisk of pneumoniaInfluenza virus infectionLogistic regression modelsHospitalized adultsICU admissionObese patientsSevere obesityInfluenza severityArtificial ventilationVirus infectionWeight categoriesObesityPneumoniaSeverityRegression modelsAdultsUnderweightPatientsAdmissionInfectionInfluenza
2014
Trends in Aortic Dissection Hospitalizations, Interventions, and Outcomes Among Medicare Beneficiaries in the United States, 2000–2011
Mody PS, Wang Y, Geirsson A, Kim N, Desai MM, Gupta A, Dodson JA, Krumholz HM. Trends in Aortic Dissection Hospitalizations, Interventions, and Outcomes Among Medicare Beneficiaries in the United States, 2000–2011. Circulation Cardiovascular Quality And Outcomes 2014, 7: 920-928. PMID: 25336626, PMCID: PMC4380171, DOI: 10.1161/circoutcomes.114.001140.Peer-Reviewed Original ResearchNational Trends in US Hospital Admissions for Hyperglycemia and Hypoglycemia Among Medicare Beneficiaries, 1999 to 2011
Lipska KJ, Ross JS, Wang Y, Inzucchi SE, Minges K, Karter AJ, Huang ES, Desai MM, Gill TM, Krumholz HM. National Trends in US Hospital Admissions for Hyperglycemia and Hypoglycemia Among Medicare Beneficiaries, 1999 to 2011. JAMA Internal Medicine 2014, 174: 1116-1124. PMID: 24838229, PMCID: PMC4152370, DOI: 10.1001/jamainternmed.2014.1824.Peer-Reviewed Original Research
2013
Trends in Aortic Valve Replacement for Elderly Patients in the United States, 1999-2011
Barreto-Filho JA, Wang Y, Dodson JA, Desai MM, Sugeng L, Geirsson A, Krumholz HM. Trends in Aortic Valve Replacement for Elderly Patients in the United States, 1999-2011. JAMA 2013, 310: 2078-2084. PMID: 24240935, PMCID: PMC4089974, DOI: 10.1001/jama.2013.282437.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAortic ValveBicuspid Aortic Valve DiseaseBlack PeopleCohort StudiesCoronary Artery BypassCross-Sectional StudiesFee-for-Service PlansFemaleHeart Defects, CongenitalHeart Valve DiseasesHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansLength of StayMaleMedicarePatient ReadmissionTreatment OutcomeUnited StatesConceptsSurgical aortic valve replacementAortic valve replacementValve replacementProcedure ratesElderly patientsCoronary artery bypass graft surgeryArtery bypass graft surgeryCross-sectional cohort studyPatients 85 yearsBypass graft surgeryHigh mortality rateCause readmissionCABG surgeryGraft surgeryOlder patientsCohort studyReadmission ratesTranscatheter optionsBlack patientsTranscatheter treatmentMechanical prosthesesThirty-dayContemporary outcomesMAIN OUTCOMEMedicare feeTrends in Hospitalization Rates and Outcomes of Endocarditis Among Medicare Beneficiaries
Bikdeli B, Wang Y, Kim N, Desai MM, Quagliarello V, Krumholz HM. Trends in Hospitalization Rates and Outcomes of Endocarditis Among Medicare Beneficiaries. Journal Of The American College Of Cardiology 2013, 62: 2217-2226. PMID: 23994421, PMCID: PMC4335801, DOI: 10.1016/j.jacc.2013.07.071.Peer-Reviewed Original ResearchSexual activity and function among middle-aged and older men and women with hypertension
Spatz ES, Canavan ME, Desai MM, Krumholz HM, Lindau ST. Sexual activity and function among middle-aged and older men and women with hypertension. Journal Of Hypertension 2013, 31: 1096-1105. PMID: 23640604, PMCID: PMC3837567, DOI: 10.1097/hjh.0b013e32835fdefa.Peer-Reviewed Original ResearchConceptsSexual problemsSexual activityHTN groupEnzyme inhibitors/angiotensin receptor blockersOlder menAntihypertensive medication classesAngiotensin receptor blockersAntihypertensive medication useAssociation of hypertensionComparative effectiveness trialCalcium channel blockersCommunity-residing adultsUntreated hypertensionMedication classesMedication groupReceptor blockersΑ-blockersMedication useHTN statusAdjusted oddsSexual functionEffectiveness trialChannel blockersHypertensionLower oddsOutcomes and Costs Associated With Robotic Colectomy in the Minimally Invasive Era
Tyler JA, Fox JP, Desai MM, Perry WB, Glasgow SC. Outcomes and Costs Associated With Robotic Colectomy in the Minimally Invasive Era. Diseases Of The Colon & Rectum 2013, 56: 458-466. PMID: 23478613, DOI: 10.1097/dcr.0b013e31827085ec.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnastomosis, SurgicalColectomyCosts and Cost AnalysisEnterostomyFemaleHospital CostsHumansIleusIntestinal FistulaIntraoperative ComplicationsLaparoscopyLength of StayMaleMiddle AgedPneumoniaPostoperative ComplicationsRetrospective StudiesRoboticsVenous ThromboembolismYoung AdultConceptsRobotic-assisted colectomyLength of stayHospital outcomesLaparoscopic colectomyOverall postoperative morbidity ratePostoperative morbidity rateLow-volume centersNationwide Inpatient SampleCost of careRobotic-assisted surgeryPotential miscodingOverall morbidityPostoperative complicationsAdult patientsIndividual complicationsLaparoscopic approachPatient characteristicsColon surgeryRetrospective reviewMorbidity rateRobotic colectomyInvasive eraInpatient SampleLaparoscopic proceduresBaseline differencesTrends in Intracranial Stenting Among Medicare Beneficiaries in the United States, 2006–2010
Gupta A, Desai MM, Kim N, Bulsara KR, Wang Y, Krumholz HM. Trends in Intracranial Stenting Among Medicare Beneficiaries in the United States, 2006–2010. Journal Of The American Heart Association 2013, 2: e000084. PMID: 23588099, PMCID: PMC3647283, DOI: 10.1161/jaha.113.000084.Peer-Reviewed Original ResearchConceptsIntracranial stentingMortality rateService beneficiariesICD-9-CM procedure codesPrincipal discharge diagnosis codeOverall hospitalization rateDischarge diagnosis codesHumanitarian Device Exemption approvalAcute care hospitalsHumanitarian Device ExemptionCare hospitalIntracranial angioplastyHospitalization ratesICS useSubarachnoid hemorrhageDiagnosis codesOperative rateProcedure ratesMedicare feeMedicare beneficiariesInsufficient evidenceICS procedureDrug AdministrationCerebral aneurysmsMedicaid Services
2012
Hospital-Level Outcomes Associated with Laparoscopic Colectomy for Cancer in the Minimally Invasive Era
Fox JP, Desai MM, Krumholz HM, Gross CP. Hospital-Level Outcomes Associated with Laparoscopic Colectomy for Cancer in the Minimally Invasive Era. Journal Of Gastrointestinal Surgery 2012, 16: 2112-2119. PMID: 22948842, PMCID: PMC3670114, DOI: 10.1007/s11605-012-2018-z.Peer-Reviewed Original ResearchConceptsLaparoscopy rateLaparoscopic colectomyShorter hospitalizationColon resectionHospital mortalityPostoperative morbidityLow postoperative morbidity rateHigher laparoscopy ratePostoperative morbidity rateRisk-standardized outcomesLow postoperative morbidityShorter hospital stayNationwide Inpatient SampleShort-term outcomesHigher procedure volumeHospital stayComparable morbidityRandomized trialsMorbidity rateInvasive eraInpatient SampleOutcomes AssociatedColectomyMortality rateProcedure volumeShort-Term Outcomes of Ablation Therapy for Hepatic Tumors: Evidence from the 2006–2009 Nationwide Inpatient Sample
Fox JP, Gustafson J, Desai MM, Hellan M, Thambi-Pillai T, Ouellette J. Short-Term Outcomes of Ablation Therapy for Hepatic Tumors: Evidence from the 2006–2009 Nationwide Inpatient Sample. Annals Of Surgical Oncology 2012, 19: 3677-3686. PMID: 22588470, DOI: 10.1245/s10434-012-2397-0.Peer-Reviewed Original ResearchConceptsProcedure-specific complicationsNationwide Inpatient SampleMetastatic liver tumorsOpen surgical approachHepatic tumorsPostoperative complicationsSurgical approachInpatient SampleLiver tumorsMultivariable logistic regression analysisTreatment-related morbidityCases/yearLogistic regression analysisResultsMost patientsTransfusion requirementsHospital morbidityAdverse eventsIntraoperative bleedingBackgroundRadiofrequency ablationHeart failureHepatic failurePatient factorsTerm outcomesLaparoscopic proceduresAblation therapyOutcomes for Mitral Valve Surgery Among Medicare Fee-for-Service Beneficiaries, 1999 to 2008
Dodson JA, Wang Y, Desai MM, Barreto-Filho JA, Sugeng L, Hashim SW, Krumholz HM. Outcomes for Mitral Valve Surgery Among Medicare Fee-for-Service Beneficiaries, 1999 to 2008. Circulation Cardiovascular Quality And Outcomes 2012, 5: 298-307. PMID: 22576847, PMCID: PMC3400109, DOI: 10.1161/circoutcomes.112.966077.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overChi-Square DistributionFee-for-Service PlansFemaleHealthcare DisparitiesHeart Valve DiseasesHeart Valve Prosthesis ImplantationHospital MortalityHospitalizationHumansLinear ModelsMaleMedicareMitral ValveOdds RatioPatient ReadmissionQuality ImprovementRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsMitral valve surgeryValve surgeryMitral valve repairFFS patientsHospitalization ratesValve repairMedicare feeMedicare Standard Analytic FilesMedicare FFS patientsRisk-standardized ratesProportion of patientsStandard Analytic FilesVital Status filesNational surveillance dataMedicare administrative dataSubstantial morbidityMortality outcomesService patientsAnalytic FilesMortality riskMortality rateSurgeryPatientsDenominator fileReadmission
2011
An Administrative Claims Measure Suitable for Profiling Hospital Performance Based on 30-Day All-Cause Readmission Rates Among Patients With Acute Myocardial Infarction
Krumholz HM, Lin Z, Drye EE, Desai MM, Han LF, Rapp MT, Mattera JA, Normand SL. An Administrative Claims Measure Suitable for Profiling Hospital Performance Based on 30-Day All-Cause Readmission Rates Among Patients With Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2011, 4: 243-252. PMID: 21406673, PMCID: PMC3350811, DOI: 10.1161/circoutcomes.110.957498.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCohort StudiesFemaleHumansInsurance Claim ReviewLogistic ModelsMaleMedicareModels, StatisticalMyocardial InfarctionOutcome and Process Assessment, Health CareOutcome Assessment, Health CarePatient ReadmissionQuality of Health CareReproducibility of ResultsRisk FactorsTime FactorsUnited StatesTrends in Comorbidity, Disability, and Polypharmacy in Heart Failure
Wong CY, Chaudhry SI, Desai MM, Krumholz HM. Trends in Comorbidity, Disability, and Polypharmacy in Heart Failure. The American Journal Of Medicine 2011, 124: 136-143. PMID: 21295193, PMCID: PMC3237399, DOI: 10.1016/j.amjmed.2010.08.017.Peer-Reviewed Original ResearchConceptsProportion of patientsHeart failureSelf-reported heart failureHeart failure populationComorbid chronic conditionsNumber of comorbiditiesNutrition Examination SurveyCare of patientsPrevalence of disabilityPhenotype of patientsComplexity of patientsMedication useRecent patientsFunctional disabilityExamination SurveyFailure populationPhysical functionPrescription medicationsPatient preferencesChronic conditionsNational HealthPatient's abilityComorbiditiesPatientsOlder individuals
2010
National Patterns of Risk-Standardized Mortality and Readmission for Acute Myocardial Infarction and Heart Failure
Bernheim SM, Grady JN, Lin Z, Wang Y, Wang Y, Savage SV, Bhat KR, Ross JS, Desai MM, Merrill AR, Han LF, Rapp MT, Drye EE, Normand SL, Krumholz HM. National Patterns of Risk-Standardized Mortality and Readmission for Acute Myocardial Infarction and Heart Failure. Circulation Cardiovascular Quality And Outcomes 2010, 3: 459-467. PMID: 20736442, PMCID: PMC3027304, DOI: 10.1161/circoutcomes.110.957613.Peer-Reviewed Original Research