2019
Eligibility for Local Therapies in Adolescents and Adults with Cutaneous Leishmaniasis from Southwestern Colombia: A Cross-Sectional Study.
Uribe-Restrepo AF, Prieto MD, Cossio A, Desai M, Castro M. Eligibility for Local Therapies in Adolescents and Adults with Cutaneous Leishmaniasis from Southwestern Colombia: A Cross-Sectional Study. American Journal Of Tropical Medicine And Hygiene 2019, 100: 306-310. PMID: 30628567, PMCID: PMC6367628, DOI: 10.4269/ajtmh.18-0643.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAntimonyAntiprotozoal AgentsChildColombiaCross-Sectional StudiesCryotherapyFemaleHumansHyperthermia, InducedLeishmania braziliensisLeishmania guyanensisLeishmaniasis, CutaneousMaleMiddle AgedParomomycinPentamidinePractice Guidelines as TopicSeverity of Illness IndexConceptsLocal therapyPan American Health OrganizationCutaneous leishmaniasisWorld Health OrganizationIndividualized risk-benefit assessmentCases of CLHealth OrganizationProportion of patientsLarge referral centerRisk-benefit assessmentDifferent treatment guidelinesMaximum lesion sizeReferral centerTreatment guidelinesSystemic drugsWHO criteriaCL patientsSectional studyLeishmania VianniaHigh burdenSevere casesLower riskLesion sizePatientsMild presentation
2018
Interventions to treat cutaneous leishmaniasis in children: A systematic review
Uribe-Restrepo A, Cossio A, Desai MM, Dávalos D, del Mar Castro M. Interventions to treat cutaneous leishmaniasis in children: A systematic review. PLOS Neglected Tropical Diseases 2018, 12: e0006986. PMID: 30550538, PMCID: PMC6310290, DOI: 10.1371/journal.pntd.0006986.Peer-Reviewed Original ResearchMeSH KeywordsAntiprotozoal AgentsClinical Trials as TopicHumansLeishmaniaLeishmaniasis, CutaneousMeglumine AntimoniatePhosphorylcholineRifampinConceptsInternational Clinical Trials Registry PlatformAdverse eventsMeglumine antimoniateCutaneous leishmaniasisSystematic reviewClinical trialsManagement of CLClinical Trials Registry PlatformOld World cutaneous leishmaniasisTreatment of CLIntralesional meglumine antimoniateOld World CLEfficacy of cryotherapySerious adverse eventsTrials Registry PlatformHarms of interventionsRisk of biasEfficacy of treatmentFull-text reviewAmerican cutaneous leishmaniasisPROSPERO International registerRegistry PlatformCohort studySystemic therapyPediatric population
2017
Clinical and parasitological factors in parasite persistence after treatment and clinical cure of cutaneous leishmaniasis
Martínez-Valencia AJ, Daza-Rivera CF, Rosales-Chilama M, Cossio A, Rincón E, Desai MM, Saravia NG, Gómez MA. Clinical and parasitological factors in parasite persistence after treatment and clinical cure of cutaneous leishmaniasis. PLOS Neglected Tropical Diseases 2017, 11: e0005713. PMID: 28704369, PMCID: PMC5526576, DOI: 10.1371/journal.pntd.0005713.Peer-Reviewed Original ResearchConceptsCutaneous leishmaniasisParasite persistencePercent of patientsInitiation of treatmentEnd of treatmentViability of LeishmaniaDisease reactivationTonsillar mucosaClinical cureClinical resolutionTreatment initiationProtective immunityMeglumine antimoniatePersistent infectionMucosal tissuesPrevious episodesTherapeutic cureParasitological factorsProtective factorsPatientsParasitological parametersTreatmentLeishmaniasisWeeksHigher proportion