2021
Randomized trial of exercise on depressive symptomatology and brain derived neurotrophic factor (BDNF) in ovarian cancer survivors: The Women's Activity and Lifestyle Study in Connecticut (WALC)
Cartmel B, Hughes M, Ercolano EA, Gottlieb L, Li F, Zhou Y, Harrigan M, Ligibel JA, von Gruenigen VE, Gogoi R, Schwartz PE, Risch HA, Lu L, Irwin ML. Randomized trial of exercise on depressive symptomatology and brain derived neurotrophic factor (BDNF) in ovarian cancer survivors: The Women's Activity and Lifestyle Study in Connecticut (WALC). Gynecologic Oncology 2021, 161: 587-594. PMID: 33773809, PMCID: PMC8085084, DOI: 10.1016/j.ygyno.2021.02.036.Peer-Reviewed Original ResearchConceptsOvarian cancer survivorsCES-D scoresCancer survivorsOvarian cancerDepressive symptomatologyAC armStage III/IV ovarian cancerBaseline CES-D scoreTrial of exerciseEpidemiologic Studies Depression ScaleOvarian cancer patientsEffects of exerciseSix-month changesPrevalent mental disordersLower depressive symptomsExercise armSerum BrainNeurotrophin factorRandomized trialsNeurotrophic factorCancer patientsLifestyle StudyDepression ScalePhysical activityDepressive symptoms
2019
Endocrine‐related quality of life in a randomized trial of exercise on aromatase inhibitor–induced arthralgias in breast cancer survivors
Baglia ML, Lin I, Cartmel B, Sanft T, Ligibel J, Hershman DL, Harrigan M, Ferrucci LM, Li F, Irwin ML. Endocrine‐related quality of life in a randomized trial of exercise on aromatase inhibitor–induced arthralgias in breast cancer survivors. Cancer 2019, 125: 2262-2271. PMID: 30840336, PMCID: PMC6731173, DOI: 10.1002/cncr.32051.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsUsual care groupCancer survivorsAdverse side effectsCare groupOverall QoLSide effectsAromatase inhibitor-induced arthralgiaCancer Therapy questionnaireExercise intervention groupTrial of exerciseShort Form SurveyPhysical exercise studiesBreast cancer treatmentOverall QOL measuresRepeated-measures analysisMild arthralgiaTreatment discontinuationExercise groupExercise interventionNonpharmacologic interventionsResistance exerciseExercise studiesAromatase inhibitorsIntervention group