Translator: A Transfer Learning Approach to Facilitate Single-Cell ATAC-Seq Data Analysis from Reference Dataset
Xu S, Skarica M, Hwang A, Dai Y, Lee C, Girgenti MJ, Zhang J. Translator: A Transfer Learning Approach to Facilitate Single-Cell ATAC-Seq Data Analysis from Reference Dataset. Journal Of Computational Biology 2022, 29: 619-633. PMID: 35584295, PMCID: PMC9464368, DOI: 10.1089/cmb.2021.0596.Peer-Reviewed Original ResearchMeSH KeywordsChromatinChromatin Immunoprecipitation SequencingData AnalysisMachine LearningSingle-Cell AnalysisTransposasesConceptsGraphic Processing Units ParallelismComplex feature interactionsDeep learning frameworkFree software packageFeature interactionsUltra-high dimensionalityLearning frameworkSoftware packageComputational efficiencySeq data analysisScATAC-seq dataDatasetReference datasetReference dataData analysisDownstream analysisCell representationRepresentationParallelismLow signalTranslatorsClusteringDimensionalityNoise ratioNonlinear relationship