2013
Olfactory ensheathing cells, but not schwann cells, proliferate and migrate extensively within moderately X‐Irradiated juvenile rat brain
Lankford KL, Brown RJ, Sasaki M, Kocsis JD. Olfactory ensheathing cells, but not schwann cells, proliferate and migrate extensively within moderately X‐Irradiated juvenile rat brain. Glia 2013, 62: 52-63. PMID: 24166823, DOI: 10.1002/glia.22583.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornAntigensCD11b AntigenCell MovementCell ProliferationCells, CulturedFemaleGlial Fibrillary Acidic ProteinGreen Fluorescent ProteinsMaleNeurogliaOlfactory MucosaOligodendrogliaProteoglycansRadiation Injuries, ExperimentalRatsRats, Sprague-DawleySchwann CellsStem Cell TransplantationConceptsJuvenile rat brainAdult spinal cordIntact adult spinal cordSchwann cellsSpinal cordRat brainAdult rat spinal cordSpinal cord lesionsRat spinal cordCord lesionsModerate radiation doseNeuronal repairPoor survivalAdult CNSUnbiased stereologyCordOECsBrainThree weeksNumber of cellsRadiation dosePermissive environmentCell migrationCellsMicroglia
2009
Unique in vivo properties of olfactory ensheathing cells that may contribute to neural repair and protection following spinal cord injury
Kocsis JD, Lankford KL, Sasaki M, Radtke C. Unique in vivo properties of olfactory ensheathing cells that may contribute to neural repair and protection following spinal cord injury. Neuroscience Letters 2009, 456: 137-142. PMID: 19429149, PMCID: PMC2713444, DOI: 10.1016/j.neulet.2008.08.093.Peer-Reviewed Original ResearchConceptsSpinal cord injuryCord injuryLow-affinity NGF receptorSchwann cell transplantationSignificant functional improvementSpinal cord resultsOlfactory receptor axonsPrecise cellular mechanismsCord resultsCell transplantationFunctional outcomeSynaptic contactsAxonal regenerationNasal mucosaFunctional improvementSpinal cordGlial cellsOlfactory bulbReceptor axonsTrophic supportNGF receptorAnimal modelsNeural repairTherapeutic candidateOECs