Featured Publications
Anti-Hypertensive Medications and Cardiovascular Events in Older Adults with Multiple Chronic Conditions
Tinetti ME, Han L, McAvay GJ, Lee DS, Peduzzi P, Dodson JA, Gross CP, Zhou B, Lin H. Anti-Hypertensive Medications and Cardiovascular Events in Older Adults with Multiple Chronic Conditions. PLOS ONE 2014, 9: e90733. PMID: 24614535, PMCID: PMC3948696, DOI: 10.1371/journal.pone.0090733.Peer-Reviewed Original ResearchConceptsMultiple chronic conditionsAnti-hypertensive treatmentCardiovascular eventsAnti-hypertensive medicationsHigh-intensity groupChronic conditionsOlder adultsHazard ratioPropensity scoreIntensity groupStandardized daily doseCommunity-living participantsPropensity score adjustmentCV eventsMedication intensityLess comorbidityDaily doseRandomized trialsMAIN OUTCOMERepresentative cohortScore adjustmentSurvey cohortRCT resultsCohortMortalityShared risk factors for falls, incontinence, and functional dependence. Unifying the approach to geriatric syndromes.
Tinetti ME, Inouye SK, Gill TM, Doucette JT. Shared risk factors for falls, incontinence, and functional dependence. Unifying the approach to geriatric syndromes. JAMA 1995, 273: 1348-53. PMID: 7715059, DOI: 10.1001/jama.273.17.1348.Peer-Reviewed Original ResearchMeSH KeywordsAccidental FallsActivities of Daily LivingAgedAged, 80 and overAnxietyCausalityCognitionCohort StudiesGeriatric AssessmentHearingHumansLogistic ModelsMultivariate AnalysisNeuropsychological TestsNutritional Physiological PhenomenaPhysical FitnessPsychomotor PerformanceRisk FactorsUrinary IncontinenceVision, OcularConceptsUrinary incontinenceGeriatric syndromesMore basic activitiesProportion of participantsRisk factorsIncontinenceDaily livingDepression scoresSyndromeGeneral communityCompensatory abilityArm strengthBasic activitiesSignificant increaseHigh anxietyImpairmentMultiple areasNew HavenYearsParticipantsFallFactorsPredisposesCohortBaseline
2009
Clinical Features to Identify Urinary Tract Infection in Nursing Home Residents: A Cohort Study
Juthani‐Mehta M, Quagliarello V, Perrelli E, Towle V, Van Ness PH, Tinetti M. Clinical Features to Identify Urinary Tract Infection in Nursing Home Residents: A Cohort Study. Journal Of The American Geriatrics Society 2009, 57: 963-970. PMID: 19490243, PMCID: PMC2692075, DOI: 10.1111/j.1532-5415.2009.02227.x.Peer-Reviewed Original ResearchConceptsUrinary tract infectionNursing home residentsClinical featuresHome residentsCohort studyTract infectionsMental statusPresence of dysuriaObservational cohort studyArea nursing homesUrine culturePyuriaClinical definitionBacteriuriaHigh riskLower riskDiagnostic uncertaintyNursing homesCombined outcomeDysuriaInfectionUrineOutcomesEpisodesRisk
2000
Environmental Hazards and the Risk of Nonsyncopal Falls in the Homes of Community-Living Older Persons
Gill T, Williams C, Tinetti M. Environmental Hazards and the Risk of Nonsyncopal Falls in the Homes of Community-Living Older Persons. Medical Care 2000, 38: 1174-1183. PMID: 11186296, DOI: 10.1097/00005650-200012000-00004.Peer-Reviewed Original ResearchConceptsNonsyncopal fallsOlder personsCommunity-living older personsProspective cohort studyBalance/gaitYears of ageFall calendarsCohort studyResearch nursesRoom assessmentFall preventionRelative riskSlip hazardsConsistent associationNumber of participantsRiskFace validityPhone callsHigh face validityProbability sampleAgeAssociationFallYearsStandard instruments
1999
The Combined Effects of Baseline Vulnerability and Acute Hospital Events on the Development of Functional Dependence Among Community-Living Older Persons
Gill T, Williams C, Tinetti M. The Combined Effects of Baseline Vulnerability and Acute Hospital Events on the Development of Functional Dependence Among Community-Living Older Persons. The Journals Of Gerontology Series A 1999, 54: m377-m383. PMID: 10462171, DOI: 10.1093/gerona/54.7.m377.Peer-Reviewed Original ResearchConceptsCommunity-living older personsValidation cohortDevelopment cohortOlder personsBaseline vulnerabilityHospital eventsPopulation-based cohort studyAcute care hospital admissionsCommunity-living personsHigh-risk groupSkilled nursing facilitiesYears of ageCohort studyHospital admissionPrimary outcomeComparable personsNew disabilityDaily livingNursing facilitiesCohortCognitive statusHigh-vulnerability groupPrecipitating eventsPhysical performanceAdmission
1998
Development of a Test Battery to Identify Older Drivers at Risk for Self‐Reported Adverse Driving Events
Marottoli R, Richardson E, Stowe M, Miller E, Brass L, Cooney L, Tinetti M. Development of a Test Battery to Identify Older Drivers at Risk for Self‐Reported Adverse Driving Events. Journal Of The American Geriatrics Society 1998, 46: 562-568. PMID: 9588368, DOI: 10.1111/j.1532-5415.1998.tb01071.x.Peer-Reviewed Original ResearchConceptsAdverse driving eventsFunctional abilityTest batteryLimited neck rotationSafety cohortAdverse eventsCohort studyVisual acuityNumber cancellation taskOutcome measuresNeck rotationMean periodParticipants' homesOlder personsClinician's officeParticipants' historySafety interviewsCohortBattery of testsPossible interventionsEtiology of impairmentsProbability sampleImpairmentOlder driversCharacteristic analysisFactors Associated With Six‐Month Mortality in Recipients of Community‐Based Long‐Term Care
Fried T, Pollack D, Tinetti M. Factors Associated With Six‐Month Mortality in Recipients of Community‐Based Long‐Term Care. Journal Of The American Geriatrics Society 1998, 46: 193-197. PMID: 9475448, DOI: 10.1111/j.1532-5415.1998.tb02538.x.Peer-Reviewed Original ResearchConceptsSix-month mortalityShort-term mortalityPresence of cancerCommunity-based long-term careLong-term careHeart diseaseChronic obstructive pulmonary diseaseNutritional problemsObstructive pulmonary diseaseSevere cognitive impairmentCommunity-based waiverCohort studyPulmonary diseaseHomecare programMortality registryMale sexFunctional impairmentClinical dataAdmission assessmentRoutine assessmentCognitive impairmentHealth statusMultivariate analysisCognitive statusMortality
1997
Self-Report versus State Records for Identifying Crashes Among Older Drivers
Marottoli R, Cooney L, Tinetti M. Self-Report versus State Records for Identifying Crashes Among Older Drivers. The Journals Of Gerontology Series A 1997, 52A: m184-m187. PMID: 9158561, DOI: 10.1093/gerona/52a.3.m184.Peer-Reviewed Original ResearchMeSH KeywordsAccidents, TrafficAgedAgingCohort StudiesFemaleForms and Records ControlHumansMaleSelf DisclosureState GovernmentA Predictive Model for ADL Dependence in Community‐Living Older Adults Based on a Reduced Set of Cognitive Status Items
Gill T, Williams C, Richardson E, Berkman L, Tinetti M. A Predictive Model for ADL Dependence in Community‐Living Older Adults Based on a Reduced Set of Cognitive Status Items. Journal Of The American Geriatrics Society 1997, 45: 441-445. PMID: 9100712, DOI: 10.1111/j.1532-5415.1997.tb05168.x.Peer-Reviewed Original ResearchConceptsADL dependenceDevelopment cohortValidation cohortPresence of impairmentsPopulation-based cohort studyMini-Mental State Examination (MMSE) itemCommunity-living older adultsCommunity-living personsSelf-reported ADLOlder person's riskYears of ageCohort studyResearch nursesMultivariable analysisRisk groupsBaseline interviewInitial cohortStratified subjectsSeparate cohortCohortPerson's riskGeneral communityOlder adultsCognitive AssessmentComparable subjects
1996
A Multifactorial Approach to Reducing Injurious Falls
King M, Tinetti M. A Multifactorial Approach to Reducing Injurious Falls. Clinics In Geriatric Medicine 1996, 12: 745-759. PMID: 8890114, DOI: 10.1016/s0749-0690(18)30199-x.Peer-Reviewed Original Research
1995
The Contribution of Predisposing and Situational Risk Factors to Serious Fall Injuries
Tinetti M, Doucette J, Claus E. The Contribution of Predisposing and Situational Risk Factors to Serious Fall Injuries. Journal Of The American Geriatrics Society 1995, 43: 1207-1213. PMID: 7594153, DOI: 10.1111/j.1532-5415.1995.tb07395.x.Peer-Reviewed Original ResearchConceptsSerious fall injuriesRisk factorsFall injuriesSerious injuriesSituational risk factorsLower body mass indexPercentage of fallersBody mass indexLoss of consciousnessMulticomponent intervention programPhysical performance measuresFirst fallRisk of injuryCohort studyInjury overallPrimary outcomeMass indexHead injuryJoint dislocationFemale genderHome assessmentCognitive impairmentPreventive programsMultivariate analysisInjuryRisk Factors for Serious Injury During Falls by Older Persons in the Community
Tinetti M, Doucette J, Claus E, Marottoli R. Risk Factors for Serious Injury During Falls by Older Persons in the Community. Journal Of The American Geriatrics Society 1995, 43: 1214-1221. PMID: 7594154, DOI: 10.1111/j.1532-5415.1995.tb07396.x.Peer-Reviewed Original ResearchConceptsSerious fall injuriesFall injury eventsFall injuriesOlder personsRisk factorsInjury eventsLower body mass indexCommunity-living personsBody mass indexSerious injuriesFall calendarsHospital recordsMass indexGait impairmentChronic conditionsEmergency roomFemale genderOlder fallersInjury dataCognitive impairmentInjuryTelephone interviewsPrevention effortsIdentifiable factorsOnly subjectsAssessing Risk for the Onset of Functional Dependence Among Older Adults: The Role of Physical Performance
Gill T, Williams C, Tinetti M. Assessing Risk for the Onset of Functional Dependence Among Older Adults: The Role of Physical Performance. Journal Of The American Geriatrics Society 1995, 43: 603-609. PMID: 7775716, DOI: 10.1111/j.1532-5415.1995.tb07192.x.Peer-Reviewed Original ResearchConceptsCommunity-dwelling adultsBasic ADLPhysical performanceOlder adultsMain outcome eventTimed testsPhysical performance testsChair standNew disabilityBaseline interviewOutcome eventsCohort membersDaily livingHigh riskRepresentative cohortRate of dependenceOlder personsRisk assessment strategiesADLRapid gaitBasic activitiesComplete dataAdultsRiskOnset
1993
A predictive index for functional decline in hospitalized elderly medical patients
Inouye S, Wagner D, Acampora D, Horwitz R, Cooney L, Hurst L, Tinetti M. A predictive index for functional decline in hospitalized elderly medical patients. Journal Of General Internal Medicine 1993, 8: 645-652. PMID: 8120679, DOI: 10.1007/bf02598279.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overChi-Square DistributionCohort StudiesConnecticutFemaleGeriatric AssessmentHospital Bed Capacity, 500 and overHospitals, UniversityHumansLikelihood FunctionsMaleMultivariate AnalysisPrevalenceProportional Hazards ModelsProspective StudiesReproducibility of ResultsRisk FactorsSingle-Blind MethodConceptsFunctional declineRisk factorsMedical patientsValidation cohortDevelopment cohortHospitalized elderly medical patientsIndependent baseline risk factorsLow social activity levelNumber of RFsPredictive indexBaseline risk factorsGeneral medical wardsProspective cohort studyGeneral medical patientsHigh-risk groupUniversity Teaching HospitalElderly medical patientsRisk stratification systemNursing home placementRate of deathSocial activity levelsComparable patientsCohort studyElderly patientsMedical wards