Embryonic implantation in mice is blocked by interleukin-1 receptor antagonist
Simón C, Frances A, Piquette G, Danasouri I, Zurawski G, Dang W, Polan M. Embryonic implantation in mice is blocked by interleukin-1 receptor antagonist. Endocrinology 1994, 134: 521-528. DOI: 10.1210/en.134.2.521.Peer-Reviewed Original ResearchIL-1R tIRhIL-1raReceptor antagonistRecombinant human IL-1 receptor antagonistEmbryonic implantationHuman IL-1 receptor antagonistMouse embryosIL-1 receptor antagonistInterleukin-1 receptor antagonistEndometrial lumenal epitheliumInterleukin-1 receptor type IEndometrium in vivoIncreasing concentrations of rhIL-1raFisher's exact testReceptor type IPregnancy days 3Fibronectin-coated platesBlastocyst formationBlastocyst stagePeriimplantation periodMigration in vitroLumenal epitheliumIL-1raPregnancy failureEmbryonic attachment