2022
High rates of macrolide and fluoroquinolone resistance in human campylobacteriosis in the Middle East and North Africa
Dabbousi A, Osman M, Dabboussi F, Hamze M. High rates of macrolide and fluoroquinolone resistance in human campylobacteriosis in the Middle East and North Africa. Future Microbiology 2022, 17: 957-967. PMID: 35796073, DOI: 10.2217/fmb-2021-0302.Peer-Reviewed Original ResearchConceptsHuman campylobacteriosisRoutine stool cultureBacterial gastrointestinal infectionsClinical laboratoriesIncidence of campylobacteriosisPaucity of dataMain causative agentStool culturesGastrointestinal infectionsDiarrheal patientsMicrobiological diagnosisClinical importanceFluoroquinolone resistanceInfection prevalenceAntimicrobial resistanceZoonotic diseaseCausative agentCampylobacteriosisHigh rateAlarming ratePatientsCritical needEpidemiologyInfectionPrevalence
2019
Plasmid-mediated quinolone resistance: Mechanisms, detection, and epidemiology in the Arab countries
Yassine I, Rafei R, Osman M, Mallat H, Dabboussi F, Hamze M. Plasmid-mediated quinolone resistance: Mechanisms, detection, and epidemiology in the Arab countries. Infection Genetics And Evolution 2019, 76: 104020. PMID: 31493557, DOI: 10.1016/j.meegid.2019.104020.Peer-Reviewed Original ResearchConceptsQuinolone resistance mechanismsQuinolone resistancePlasmid-mediated quinolone resistance mechanismsPlasmid-mediated genesImportant antimicrobial classesResistance mechanismsTreatment failureEnterobacterial infectionsPMQR genesStewardship effortsAntimicrobial classesPMQRIrrational useMultiple mechanismsHigh rateEpidemiologyQuinolonesCommon associationCrucial antibioticsEnvironmental isolatesMethod of detectionEnterobacteriaceaeAntibiotic resistance genesAnimalsResistance genes
2015
Initial Data on the Molecular Epidemiology of Cryptosporidiosis in Lebanon
Osman M, Safadi D, Benamrouz S, Guyot K, Dei-Cas E, Aliouat E, Creusy C, Mallat H, Hamze M, Dabboussi F, Viscogliosi E, Certad G. Initial Data on the Molecular Epidemiology of Cryptosporidiosis in Lebanon. PLOS ONE 2015, 10: e0125129. PMID: 25950832, PMCID: PMC4423932, DOI: 10.1371/journal.pone.0125129.Peer-Reviewed Original ResearchConceptsMajor public health problemPublic health problemZiehl-Neelsen stainingCryptosporidium sppC. parvum subtypesGastrointestinal disordersRare subtypeImmunocompromised personsOverall prevalenceGastrointestinal tractHealth problemsFecal specimensMolecular epidemiologyEpidemiologyC. parvumPositive samplesPatientsHigh rateC. hominisInfectionPrevalenceSubtypesGp60 locusNorth LebanonCryptosporidium