2023
Genomic analysis of Shigella isolates from Lebanon reveals marked genetic diversity and antimicrobial resistance
Yassine I, Rafei R, de la Gandara M, Osman M, Fabre L, Dabboussi F, Hamze M, Weill F. Genomic analysis of Shigella isolates from Lebanon reveals marked genetic diversity and antimicrobial resistance. Microbial Genomics 2023, 9: 001157. PMID: 38100171, PMCID: PMC10763507, DOI: 10.1099/mgen.0.001157.Peer-Reviewed Original ResearchConceptsExtended-spectrum beta-lactamase genesThird-generation cephalosporinsMultidrug resistance phenotypeBeta-lactamase genesAntimicrobial resistance determinantsPrevalent serogroupsClinical isolatesQuinolone resistanceDNA gyrase genesAntimicrobial resistanceResistance determinantsCTXResistance phenotypeAmino acid substitutionsGyrase genesIsolatesNorth LebanonFirst studyAcid substitutionsPoint mutationsGenomic analysisCephalosporins
2021
Molecular Characterization of Antimicrobial Resistance and Virulence Genes of Bacterial Pathogens from Bovine and Caprine Mastitis in Northern Lebanon
Abboud Z, Galuppo L, Tolone M, Vitale M, Puleio R, Osman M, Loria G, Hamze M. Molecular Characterization of Antimicrobial Resistance and Virulence Genes of Bacterial Pathogens from Bovine and Caprine Mastitis in Northern Lebanon. Microorganisms 2021, 9: 1148. PMID: 34071800, PMCID: PMC8228836, DOI: 10.3390/microorganisms9061148.Peer-Reviewed Original ResearchMolecular characterizationMatrix-assisted laser desorptionGram-positive bacteriaResistance genesGenesPolymerase chain reactionPhylogenetic group B1Virulence factorsVirulence genesAntimicrobial resistance genesBacterial pathogensToxin genesLaser desorptionMastitis-causing pathogensNegative bacteriaBeta-lactamase genesFlight mass spectrometryBacterial identificationBacteriaQuadruplex PCR methodSymptoms of mastitisDairy animalsPhylogenetic typingIsolatesPathogens