2022
Laboratory Diagnosis for SARS-CoV-2 Infection
Christensen BB, Azar MM, Turbett SE. Laboratory Diagnosis for SARS-CoV-2 Infection. Infectious Disease Clinics Of North America 2022, 36: 327-347. PMID: 35636903, PMCID: PMC9141924, DOI: 10.1016/j.idc.2022.02.002.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionClinical syndromeMolecular testingPatient's clinical syndromeReverse transcriptase-polymerase chain reactionOptimal diagnostic testCOVID-19 infectionSymptom onsetAcute infectionAntigen testingSerologic testingAcute diagnosisPolymerase chain reactionLaboratory diagnosisDiagnostic testsInfectionChain reactionDiagnosisSyndromeTesting
2021
Increased Detection of Mycobacterium tuberculosis Disease Using a Tissue-Based Laboratory-Developed Polymerase Chain Reaction Assay Compared to Standard Diagnostics.
Mackow NA, Abi-Raad R, Kerantzas CA, Hui P, Malinis M, Azar MM. Increased Detection of Mycobacterium tuberculosis Disease Using a Tissue-Based Laboratory-Developed Polymerase Chain Reaction Assay Compared to Standard Diagnostics. American Journal Of Tropical Medicine And Hygiene 2021, 105: 1657-1661. PMID: 34544041, PMCID: PMC8641361, DOI: 10.4269/ajtmh.21-0104.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCulture TechniquesFemaleHumansLungLymph NodesMaleMiddle AgedMycobacterium tuberculosisPleuraReal-Time Polymerase Chain ReactionReference StandardsRetrospective StudiesSensitivity and SpecificitySputumTuberculosisTuberculosis, Lymph NodeTuberculosis, Multidrug-ResistantTuberculosis, PleuralTuberculosis, PulmonaryConceptsComposite reference standardMTB PCRAFB cultureMycobacterium tuberculosisPolymerase chain reactionAcid-fast bacilli smearMycobacterium tuberculosis diseasePositive AFB cultureChain reactionReal-time polymerase chain reactionStandard diagnosticsBacilli smearMTB casesTuberculosis diseaseClinical sensitivityLong turnaround timeXpertClinical performanceReference standardPCRVariable sensitivityTurnaround timeLymphPatientsTuberculosis
2020
Diagnostic Testing of COVID-19 in Solid Organ Transplantation: Current Clinical Application and Future Strategies
Trubin PA, Azar MM, Malinis M. Diagnostic Testing of COVID-19 in Solid Organ Transplantation: Current Clinical Application and Future Strategies. Current Transplantation Reports 2020, 7: 390-398. PMID: 33134033, PMCID: PMC7585558, DOI: 10.1007/s40472-020-00307-w.Peer-Reviewed Original ResearchSARS-CoV-2 infectionSolid organ transplantationInfection prevention practicesOrgan transplantationTransplant recipientsPolymerase chain reactionAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSolid organ transplant recipientsSyndrome coronavirus 2 infectionPrevention practicesCOVID-19 pandemicRecipient suitabilityCoronavirus 2 infectionOrgan transplant recipientsChain reactionCoronavirus disease 2019SARS-CoV-2Current clinical applicationsDiagnostic testing strategiesCOVID-19 diagnosticsMitigation of infectionPurpose of ReviewWhileOptimal donorViral kinetics