2016
Spider Silk Peptide Is a Compact, Linear Nanospring Ideal for Intracellular Tension Sensing
Brenner MD, Zhou R, Conway DE, Lanzano L, Gratton E, Schwartz MA, Ha T. Spider Silk Peptide Is a Compact, Linear Nanospring Ideal for Intracellular Tension Sensing. Nano Letters 2016, 16: 2096-2102. PMID: 26824190, PMCID: PMC4851340, DOI: 10.1021/acs.nanolett.6b00305.Peer-Reviewed Original ResearchConceptsSingle-molecule fluorescence-force spectroscopyFluorescence-force spectroscopyFluorescence resonance energy transferResonance energy transferRodlike structureSensor constructsShort peptidesIndividual chainsAccessible forcesEnergy transferSilk peptideCell imagingSpider silk proteinsBiological systemsRemarkable elasticitySilk proteinsFRETPN.PeptidesSpider silkPolymersSpectroscopyRecent developmentsForce sensitivityWide range
1982
A new radioactive cross-linking reagent for studying the interactions of proteins.
Schwartz M, Das O, Hynes R. A new radioactive cross-linking reagent for studying the interactions of proteins. Journal Of Biological Chemistry 1982, 257: 2343-2349. PMID: 7061425, DOI: 10.1016/s0021-9258(18)34928-7.Peer-Reviewed Original ResearchConceptsCross-linking reagentInteraction of proteinsChemical cross-linking reagentsBinding of gelatinCovalent derivativesChemical behaviorSecond moleculeNeighboring macromoleculesN-succinimidyl propionateReagentsHigh yieldsBiological systemsNitro-4DerivativesBiological conditionsPhotolysisMacromoleculesMoleculesInteractionGelatinSituSurfaceYield