2017
Reprimo tissue-specific expression pattern is conserved between zebrafish and human
Figueroa RJ, Carrasco-Avino G, Wichmann IA, Lange M, Owen GI, Siekmann AF, Corvalán AH, Opazo JC, Amigo JD. Reprimo tissue-specific expression pattern is conserved between zebrafish and human. PLOS ONE 2017, 12: e0178274. PMID: 28562620, PMCID: PMC5451059, DOI: 10.1371/journal.pone.0178274.Peer-Reviewed Original ResearchConceptsTissue-specific expression patternsExpression patternsGene familyExpression profilesSpatiotemporal expression profilesSitu hybridizationP53-mediated cell cycle arrestG2/M.Tumor suppressor geneUnique expression profileCell cycle arrestZebrafish developmentPhylogenetic analysisMost speciesMalignant tumor progressionGene transcriptsZebrafishProtein productsSpatiotemporal expressionCycle arrestReprimoCentral nervous systemPathological roleModel systemRT-qPCR
2014
A new paradigm for transcription factor TFIIB functionality
Gelev V, Zabolotny JM, Lange M, Hiromura M, Yoo SW, Orlando JS, Kushnir A, Horikoshi N, Paquet E, Bachvarov D, Schaffer PA, Usheva A. A new paradigm for transcription factor TFIIB functionality. Scientific Reports 2014, 4: 3664. PMID: 24441171, PMCID: PMC3895905, DOI: 10.1038/srep03664.Peer-Reviewed Original ResearchMeSH KeywordsAcetylationAnimalsBinding SitesCell CycleCell LineDatasets as TopicGene ExpressionGene Expression ProfilingGene Expression RegulationGene Expression Regulation, ViralGene Knockdown TechniquesGene SilencingGenes, LethalGenome, HumanHerpesvirus 1, HumanHumansOrgan SpecificityProtein BindingRNA Polymerase IITranscription Factor TFIIBTranscription Initiation SiteTranscription, GeneticTranscriptomeConceptsTranscription initiationGene expressionGeneral transcription factor TFIIBTranscription factor TFIIBRNA polymerase IIGlobal gene expressionHuman gene expressionPolymerase IIGene transcriptionBioinformatics analysisBioinformatics studiesGene promoterHuman promotersCellular functionalityMitotic chromatidsTFIIBCell linesTranscriptionPromoterExpression