2012
Development and refinement of a technique using a medical radiation therapy facility to irradiate immunodeficient mice bearing xenografted human tumours
Baro M, de Llobet L, Modolell I, Guedea F, Visa J, Balart J. Development and refinement of a technique using a medical radiation therapy facility to irradiate immunodeficient mice bearing xenografted human tumours. Laboratory Animals 2012, 46: 345-348. PMID: 22723647, DOI: 10.1258/la.2012.011147.Peer-Reviewed Original Research
2011
The use of caspase inhibitors in pulsed-field gel electrophoresis may improve the estimation of radiation-induced DNA repair and apoptosis
Balart J, Pueyo G, de Llobet L, Baro M, Sole X, Marin S, Casanovas O, Mesia R, Capella G. The use of caspase inhibitors in pulsed-field gel electrophoresis may improve the estimation of radiation-induced DNA repair and apoptosis. Radiation Oncology 2011, 6: 6. PMID: 21235815, PMCID: PMC3025872, DOI: 10.1186/1748-717x-6-6.Peer-Reviewed Original ResearchConceptsRadiation-induced DNA repairDNA repairCaspase inhibitorsDNA double-strand break repairChemical caspase inhibitorsSpontaneous DNA breakageDNA fragmentationDouble-strand break repairInterference of apoptosisSpecific caspase inhibitorsPulsed-field gel electrophoresisSpontaneous DNA fragmentationGel electrophoresisCell fateBreak repairDNA fragmentsApoptosis inhibitorH2AX activationAgarose plugsDNA breakageApoptosis inhibitionFunctional assaysCaspase-3ApoptosisCell cultures