Signal recognition particle receptor-β (SR-β) coordinates cotranslational N-glycosylation
Phoomak C, Rinis N, Baro M, Shrimal S, Bennett D, Shaffer S, Lehrman M, Gilmore R, Contessa J. Signal recognition particle receptor-β (SR-β) coordinates cotranslational N-glycosylation. Science Advances 2023, 9: eade8079. PMID: 36921042, PMCID: PMC10017033, DOI: 10.1126/sciadv.ade8079.Peer-Reviewed Original ResearchConceptsSignal recognition particle receptorN-glycosylationProper protein foldingCotranslational N-glycosylationOligosaccharyltransferase complexPosttranslational modificationsProtein foldingSecretory compartmentsHigh-throughput screeningEndoplasmic reticulumCellular localizationUnrecognized functionChemical probesProteinTransloconReceptorsSubunitsFoldingReticulumMutationsPhenotypeCompartmentsAssemblyCellsLocalization