Simvastatin Enhances the Effects of Radiotherapy and Cetuximab on a Cell Line (FaDu) Derived from a Squamous Cell Carcinoma of Head and Neck
de Llobet L, Baro M, Mesia R, Balart J. Simvastatin Enhances the Effects of Radiotherapy and Cetuximab on a Cell Line (FaDu) Derived from a Squamous Cell Carcinoma of Head and Neck. Translational Oncology 2014, 7: 513-522. PMID: 25171892, PMCID: PMC4202798, DOI: 10.1016/j.tranon.2014.02.008.Peer-Reviewed Original ResearchEpidermal growth factor receptorExtracellular signal-regulated kinases 1Signal-regulated kinases 1Cell linesEfficient epidermal growth factor receptorPhosphorylated extracellular signal-regulated kinases 1Growth factor receptorA431 cell lineSignal transducerKinase BKinase 1Cancer progressionSynthesis of cholesterolFactor receptorCaspase-3Cell proliferationFaDu cellsCell culturesStatin simvastatinClonogenic assayTumor growthWound healingIsoprenoidsOncoproteinApoptosis