2020
Can NSAIDs Be Used Safely for Analgesia in Patients with CKD?: COMMENTARY.
Baker ML, Perazella MA. Can NSAIDs Be Used Safely for Analgesia in Patients with CKD?: COMMENTARY. Kidney360 2020, 1: 1192-1194. PMID: 35372870, PMCID: PMC8815502, DOI: 10.34067/kid.0004652020.Commentaries, Editorials and LettersAnalgesiaAnti-Inflammatory Agents, Non-SteroidalHumansPainPain ManagementRenal Insufficiency, ChronicNSAIDs in CKD: Are They Safe?
Baker M, Perazella MA. NSAIDs in CKD: Are They Safe? American Journal Of Kidney Diseases 2020, 76: 546-557. PMID: 32479922, DOI: 10.1053/j.ajkd.2020.03.023.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAnti-Inflammatory Agents, Non-SteroidalHumansKidney DiseasesPainRenal Insufficiency, ChronicConceptsNonsteroidal anti-inflammatory drugsChronic kidney diseaseGlomerular filtration rateFiltration rateRisk factorsHigh pain burdenAcute kidney injuryManagement of painAnti-inflammatory drugsCKD populationNSAID useKidney injuryPain burdenPain controlHeart failureComorbid conditionsElectrolyte derangementsKidney diseaseSafety dataDrug effectsPatientsIndividualized basisDrug metabolismProgressive lossCautious use
2001
Selective cyclooxygenase-2 inhibitors: a pattern of nephrotoxicity similar to traditional nonsteroidal anti-inflammatory drugs
Perazella M, Tray K. Selective cyclooxygenase-2 inhibitors: a pattern of nephrotoxicity similar to traditional nonsteroidal anti-inflammatory drugs. The American Journal Of Medicine 2001, 111: 64-67. PMID: 11448662, DOI: 10.1016/s0002-9343(01)00757-4.Peer-Reviewed Original ResearchCOX-2 Inhibitors and the Kidney
Perazella M. COX-2 Inhibitors and the Kidney. Hospital Practice 2001, 36: 43-56. PMID: 11263799, DOI: 10.3810/hp.2001.03.230.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedAged, 80 and overAnti-Inflammatory Agents, Non-SteroidalCelecoxibCyclooxygenase InhibitorsFemaleHumansKidneyProstaglandinsProtein IsoformsPyrazolesSulfonamidesNSAIDs and the Kidney Revisited: Are Selective Cyclooxygenase-2 Inhibitors Safe?
Eras J, Perazella M. NSAIDs and the Kidney Revisited: Are Selective Cyclooxygenase-2 Inhibitors Safe? The American Journal Of The Medical Sciences 2001, 321: 181-190. PMID: 11269794, DOI: 10.1097/00000441-200103000-00005.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Inflammatory Agents, Non-SteroidalCyclooxygenase 1Cyclooxygenase 2Cyclooxygenase 2 InhibitorsCyclooxygenase InhibitorsHumansIsoenzymesKidneyMembrane ProteinsProstaglandin-Endoperoxide SynthasesProstaglandinsRenal InsufficiencyConceptsNonsteroidal anti-inflammatory drugsCOX-2 selective inhibitorsSelective cyclooxygenase-2 inhibitorRenal effectsCyclooxygenase-2 inhibitorNonselective nonsteroidal anti-inflammatory drugsSelective nonsteroidal anti-inflammatory drugsSelective COX-2 inhibitorsAdverse renal effectsBaseline patient characteristicsAdverse gastrointestinal effectsCOX-1/COXCyclooxygenase enzyme activityAnti-inflammatory drugsCOX-2 inhibitorsCOX-2 enzymePatient characteristicsGastrointestinal effectsChronic painGastric erosionsInflammatory conditionsClinical studiesClinical investigationKidney tissueKidney
1998
Drug-Induced Acute Tubulointerstitial Nephritis: The Clinical Spectrum
Cruz D, Perazella M. Drug-Induced Acute Tubulointerstitial Nephritis: The Clinical Spectrum. Hospital Practice 1998, 33: 151-164. PMID: 9484301, DOI: 10.1080/21548331.1998.11443642.Peer-Reviewed Original ResearchMeSH KeywordsAdrenal Cortex HormonesAnti-Bacterial AgentsAnti-Inflammatory Agents, Non-SteroidalAnticonvulsantsBiopsyDiureticsGallium RadioisotopesHumansNephritis, Interstitial
1997
Acute renal failure and ketorolac.
Buller G, Perazella M. Acute renal failure and ketorolac. Annals Of Internal Medicine 1997, 127: 493-4. PMID: 9313014, DOI: 10.7326/0003-4819-127-6-199709150-00022.Peer-Reviewed Original Research
1993
NSAID Nephrotoxicity Revisited: Acute Renal Failure Due to Parenteral Ketorolac
PERAZELLA M, BULLER G. NSAID Nephrotoxicity Revisited: Acute Renal Failure Due to Parenteral Ketorolac. Southern Medical Journal 1993, 86: 1421-1424. PMID: 8272928, DOI: 10.1097/00007611-199312000-00025.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAdultAgedAnti-Inflammatory Agents, Non-SteroidalFemaleHumansInjections, IntramuscularKetorolacMaleTolmetinConceptsNSAID nephrotoxicityAcute renal failureSevere postoperative painMajor surgical proceduresKetorolac therapyParenteral ketorolacRenal hypoperfusionNonsurgical patientsPostoperative painRenal insufficiencyElderly patientsNonnarcotic analgesicsOral NSAIDsRenal failureRenal functionSuch patientsUrine outputSurgical proceduresKetorolacPatientsMedical literatureNephrotoxicitySuch proceduresSame degreeHypoperfusion