2000
Are selective COX-2 inhibitors nephrotoxic?
Perazella M, Eras J. Are selective COX-2 inhibitors nephrotoxic? American Journal Of Kidney Diseases 2000, 35: 937-940. PMID: 10793030, DOI: 10.1016/s0272-6386(00)70266-6.Peer-Reviewed Original ResearchConceptsHigh-risk patientsRenal insufficiencySelective cyclooxygenase-2 enzyme inhibitorsSuch high-risk patientsNonsteroidal anti-inflammatory drugsSelective COX-2 inhibitorsChronic renal impairmentChronic renal insufficiencyAcute renal failureAcute renal insufficiencyAdverse gastrointestinal effectsCyclooxygenase-2 enzyme inhibitorsAnti-inflammatory drugsCourse of therapyCOX-2 inhibitorsPain syndromeRenal impairmentRenal failureGastrointestinal effectsNephrotoxic potentialInflammatory diseasesEnzyme inhibitorsPatientsInsufficiencyInhibitors
1999
Crystal-induced acute renal failure
Perazella M. Crystal-induced acute renal failure. The American Journal Of Medicine 1999, 106: 459-465. PMID: 10225250, DOI: 10.1016/s0002-9343(99)00041-8.Peer-Reviewed Original ResearchConceptsAcute renal failureRenal insufficiencyRenal failureVolume repletionAppropriate drug dosingIntrarenal crystal depositionAcute renal insufficiencyIntravascular volume depletionAdditional risk factorsHigh urinary flowDialytic supportUrinary flowRisk factorsVolume depletionDrug dosingDrug dosesCrystal depositionIntratubular precipitationInsufficiencyUrineMedicationsRepletionFurther exposureFailureHuman urine
1998
Indinavir nephropathy in an AIDS patient with renal insufficiency and pyuria.
Perazella M, Kashgarian M, Cooney E. Indinavir nephropathy in an AIDS patient with renal insufficiency and pyuria. Clinical Nephrology 1998, 50: 194-6. PMID: 9776425.Peer-Reviewed Original ResearchConceptsRenal biopsy findingsRenal insufficiencyBiopsy findingsMild renal insufficiencyAcute renal failureIndinavir crystalsIndinavir therapyRenal failureAntiretroviral agentsUrinary obstructionAIDS patientsCellular castsPatientsPyuriaInsufficiencyRecent reportsSmall percentDiscontinuationNephropathyMedicationsSecond caseDiuresisNephrolithiasisIndinavirObstruction
1997
Renal insufficiency after intravenous immune globulin therapy: a report of two cases and an analysis of the literature.
Cayco A, Perazella M, Hayslett J. Renal insufficiency after intravenous immune globulin therapy: a report of two cases and an analysis of the literature. Journal Of The American Society Of Nephrology 1997, 8: 1788-94. PMID: 9355083, DOI: 10.1681/asn.v8111788.Peer-Reviewed Original ResearchConceptsIntravenous immune globulin therapyAcute renal failureImmune globulin therapyGlobulin therapyRenal replacement therapyNumber of complicationsIVIG treatmentRenal insufficiencyRenal failureRenal injuryIVIG preparationsSuch patientsReplacement therapyClinical disordersTherapyCases recoveryComplicationsPatientsRecurrenceWidespread useInjuryInsufficiencyAgentsCases
1993
Renal Failure and Severe Hypokalemia Associated With Acute Myelomonocytic Leukemia
Perazella M, Eisen R, Frederick W, Brown E. Renal Failure and Severe Hypokalemia Associated With Acute Myelomonocytic Leukemia. American Journal Of Kidney Diseases 1993, 22: 462-467. PMID: 8372846, DOI: 10.1016/s0272-6386(12)70154-3.Peer-Reviewed Original ResearchConceptsAcute myelomonocytic leukemiaRenal failureMyelomonocytic leukemiaRenal parenchymal infiltrationRenal tubular injuryHypokalemia AssociatedInappropriate kaliuresisMicrovascular insufficiencyRenal insufficiencySevere hypokalemiaTubular injuryParenchymal infiltrationSetting of leukemiaBlast cellsLeukemiaMetabolic perturbationsHypokalemiaVariety of mechanismsInsufficiencyFailureLeukostasisKaliuresisEtiologyInjury
1991
Can Ibuprofen Cause Acute Renal Failure in a Normal Individual? A Case of Acute Overdose
Perazella M, Buller G. Can Ibuprofen Cause Acute Renal Failure in a Normal Individual? A Case of Acute Overdose. American Journal Of Kidney Diseases 1991, 18: 600-602. PMID: 1951342, DOI: 10.1016/s0272-6386(12)80657-3.Peer-Reviewed Original ResearchConceptsNonsteroidal antiinflammatory drugsAcute renal failureRenal blood flowRenal failureAcute renal insufficiencyCase of AcuteRenal insufficiencyTubular necrosisAntiinflammatory drugsBlood flowRenal syndromeClinical situationsNormal individualsIbuprofenFailureAcutePatientsSyndromeInsufficiencyNecrosis