2008
Sequential autoantigenic determinants of the small nuclear ribonucleoprotein Sm D shared by human lupus autoantibodies and MRL Ipr/lpr antibodies
JAMES J, MAMULA M, HARLEY J. Sequential autoantigenic determinants of the small nuclear ribonucleoprotein Sm D shared by human lupus autoantibodies and MRL Ipr/lpr antibodies. Clinical & Experimental Immunology 2008, 98: 419-426. PMID: 7527740, PMCID: PMC1534503, DOI: 10.1111/j.1365-2249.1994.tb05507.x.Peer-Reviewed Original ResearchConceptsMRL-lpr/lpr miceLpr/lpr miceAutoimmune serologySLE patientsLpr micePatient seraEpitope 5Systemic lupus erythematosus (SLE) patient seraEpstein-Barr nuclear antigen 1Lupus patients' seraNuclear antigen 1Precipitin-positive seraHuman lupus autoantibodiesNormal human serumMajor antigenic regionSm DPositive patientsAutoimmune responseSm autoantigenLupus autoantibodiesNormal controlsPatientsEpitope 4Mouse serumAntigen 1
2001
Post-translational protein modifications in antigen recognition and autoimmunity
Doyle H, Mamula M. Post-translational protein modifications in antigen recognition and autoimmunity. Trends In Immunology 2001, 22: 443-449. PMID: 11473834, DOI: 10.1016/s1471-4906(01)01976-7.Peer-Reviewed Original Research
1998
Advances in autoantibodies in SLE
von Mühlen C, Chan E, Anglés-Cano E, Mamula M, Garcia-De La Torre I, Fritzler M. Advances in autoantibodies in SLE. Lupus 1998, 7: 507-514. PMID: 9863891, DOI: 10.1191/096120398678920613.Peer-Reviewed Original ResearchEpitope spreading: the role of self peptides and autoantigen processing by B lymphocytes
Mamula M, Mamula M. Epitope spreading: the role of self peptides and autoantigen processing by B lymphocytes. Immunological Reviews 1998, 164: 231-233. PMID: 9795779, DOI: 10.1111/j.1600-065x.1998.tb01223.x.Peer-Reviewed Original ResearchConceptsImmune responseB lymphocytesAutoantigen-presenting cellsProductive immune responseDiverse immune responsesAutoantigen processingAutoimmune diseasesSelf antigensImmune attackSelf constituentsAntigen leadSelf peptidesViral infectionInfectious agentsImmune systemSelf tissuesAntigenPotential roleAutoimmunityLymphocytesEpitopesConcept of epitopeCellsAgentsInfection
1994
The expression of self antigenic determinants: implications for tolerance and autoimmunity
Mamula M, Craft J. The expression of self antigenic determinants: implications for tolerance and autoimmunity. Current Opinion In Immunology 1994, 6: 882-886. PMID: 7536009, DOI: 10.1016/0952-7915(94)90008-6.Peer-Reviewed Original ResearchConceptsAntigen-presenting cellsT cellsSelf peptidesSelf antigenic determinantsT cell responsesPathogenesis of autoimmunityMajor histocompatibility moleculesNormal lymphocytesAntigen processingAntigenic determinantsHistocompatibility moleculesAutoimmunityCell surface proteinsNormal pathwayCellsPeptidesLymphocytesPathogenesis
1990
The specificity of human anti-cytochrome c autoantibodies that arise in autoimmune disease.
Mamula M, Jemmerson R, Hardin J. The specificity of human anti-cytochrome c autoantibodies that arise in autoimmune disease. The Journal Of Immunology 1990, 144: 1835-40. PMID: 1689756, DOI: 10.4049/jimmunol.144.5.1835.Peer-Reviewed Original ResearchConceptsC autoantibodiesC antibodyPresence of autoantibodiesConnective tissue diseaseSpecificity of autoantibodiesAntimitochondrial antibodiesAutoantibody responseTissue diseaseAutoimmune diseasesDisease subsetsSm autoantigenPatient seraAutoantibodiesAnimal modelsModel AgAntibodiesDiseaseSpecificityPatientsSLEAutoantigensMicePathologySerumResponse
1989
Human monoclonal anti-La antibodies. The La protein resides on a subset of Ro particles.
Mamula M, Silverman E, Laxer R, Bentur L, Isacovics B, Hardin J. Human monoclonal anti-La antibodies. The La protein resides on a subset of Ro particles. The Journal Of Immunology 1989, 143: 2923-8. PMID: 2478628, DOI: 10.4049/jimmunol.143.9.2923.Peer-Reviewed Original Research