1989
The Ro ribonucleoprotein particle: Induction of autoantibodies and the detection of Ro RNAs among species
Mamula M, O'Brien C, Harley J, Hardin J. The Ro ribonucleoprotein particle: Induction of autoantibodies and the detection of Ro RNAs among species. Clinical Immunology 1989, 52: 435-446. PMID: 2503280, DOI: 10.1016/0090-1229(89)90158-x.Peer-Reviewed Original ResearchConceptsRo RNAsInduction of autoantibodiesSystemic lupus erythematosusRo particleAnti-Ro autoantibodiesCell linesRabbit cell linesSjogren's syndromeLupus erythematosusHuman autoimmune seraRo seraImmune responseHigh titersAutoantibodiesAutoimmune seraSerumRabbit serumSolid-phase assaysRabbit antibodiesHuman cellsImmunodiffusion studiesSyndromeBovine cell linesTissue extractsPrecipitin line
1987
Implications of anti-Ro/Sjögren's syndrome A antigen autoantibody in normal sera for autoimmunity.
Gaither K, Fox O, Yamagata H, Mamula M, Reichlin M, Harley J. Implications of anti-Ro/Sjögren's syndrome A antigen autoantibody in normal sera for autoimmunity. Journal Of Clinical Investigation 1987, 79: 841-846. PMID: 3546381, PMCID: PMC424215, DOI: 10.1172/jci112892.Peer-Reviewed Original ResearchConceptsRo/SSAAnti-Ro/SSALa/SSBNormal serumAntigen autoantibodiesSjögren's syndromeAnti-Ro/Sjögren's syndromeRo/Sjögren's syndromeHealthy normal donorsSjögren's syndrome autoantibodiesPreexisting immune responseRo/SSA precipitinsTrue autoantibodiesImmune responseNormal donorsAutoantibodiesSyndromeFragments of IgG.Western immunoblotSSA levelsSerumPatientsSensitive assayLow levelsAutoimmunity