1992
Anti-Ro autoantibody with cross-reactive binding to the heavy chain of immunoglobulin G.
Mamula M, Harley J. Anti-Ro autoantibody with cross-reactive binding to the heavy chain of immunoglobulin G. The Yale Journal Of Biology And Medicine 1992, 65: 277-87. PMID: 1290272, PMCID: PMC2589586.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, AntinuclearAutoantigensBinding, CompetitiveCattleCross ReactionsCyanogen BromideEnzyme-Linked Immunosorbent AssayHumansImmunoglobulin Fab FragmentsImmunoglobulin Fc FragmentsImmunoglobulin GImmunoglobulin Heavy ChainsLupus Erythematosus, SystemicPeptide FragmentsPrecipitin TestsRabbitsRibonucleoproteinsRNA, Small CytoplasmicConceptsSystemic lupus erythematosusRo antibodiesAutoimmune diseasesCross-reactive bindingSera of patientsAnti-Ro autoantibodiesHeavy chainAnti-Ro seraFragments of IgGRo proteinLupus erythematosusCyanogen bromide digestion fragmentsAntigenic stimulusRo seraPatient seraAutoantibodiesIgGFine specificityImmunologic determinantsRo responseImmunoglobulin GSerumAntibodiesRo particleRabbit serum
1991
Importance of the immune response to the Ro/La particle in the development of congenital heart block and neonatal lupus erythematosus.
Silverman E, Mamula M, Hardin J, Laxer R. Importance of the immune response to the Ro/La particle in the development of congenital heart block and neonatal lupus erythematosus. The Journal Of Rheumatology 1991, 18: 120-4. PMID: 2023181.Peer-Reviewed Original ResearchConceptsNeonatal lupus erythematosusCongenital heart blockAnti-La antibodiesHeart blockImmune responseLupus erythematosusCutaneous neonatal lupus erythematosusAnti-U1RNP antibodiesAnti-Ro antibodiesRo antibodiesAnti-RoLa antibodiesAntibodiesErythematosusAssay techniquesPrevious studiesResponsePatientsInfantsPathogenesisWomen
1990
The specificity of human anti-cytochrome c autoantibodies that arise in autoimmune disease.
Mamula M, Jemmerson R, Hardin J. The specificity of human anti-cytochrome c autoantibodies that arise in autoimmune disease. The Journal Of Immunology 1990, 144: 1835-40. PMID: 1689756, DOI: 10.4049/jimmunol.144.5.1835.Peer-Reviewed Original ResearchConceptsC autoantibodiesC antibodyPresence of autoantibodiesConnective tissue diseaseSpecificity of autoantibodiesAntimitochondrial antibodiesAutoantibody responseTissue diseaseAutoimmune diseasesDisease subsetsSm autoantigenPatient seraAutoantibodiesAnimal modelsModel AgAntibodiesDiseaseSpecificityPatientsSLEAutoantigensMicePathologySerumResponse
1986
The Ro/SSA autoantigen as an immunogen. Some anti-Ro/SSA antibody binds IgG.
Mamula M, Fox O, Yamagata H, Harley J. The Ro/SSA autoantigen as an immunogen. Some anti-Ro/SSA antibody binds IgG. Journal Of Experimental Medicine 1986, 164: 1889-1901. PMID: 3097237, PMCID: PMC2188496, DOI: 10.1084/jem.164.6.1889.Peer-Reviewed Original Research