2019
Pathobiology of inherited biliary diseases: a roadmap to understand acquired liver diseases
Fabris L, Fiorotto R, Spirli C, Cadamuro M, Mariotti V, Perugorria MJ, Banales JM, Strazzabosco M. Pathobiology of inherited biliary diseases: a roadmap to understand acquired liver diseases. Nature Reviews Gastroenterology & Hepatology 2019, 16: 497-511. PMID: 31165788, PMCID: PMC6661007, DOI: 10.1038/s41575-019-0156-4.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCystic fibrosis-related liver diseaseFibropolycystic liver diseaseLiver diseasePolycystic liver diseaseBiliary repairAlagille syndromeEpithelial toll-like receptor 4Toll-like receptor 4Acquired liver diseasesGut-derived productsPrimary sclerosing cholangitisDuct epithelial cellsSclerosing cholangitisΒ-catenin signalingPortal fibrosisBiliary diseaseIL-1βUnknown etiologyDependent cytokinesReceptor 4Peribiliary inflammationRole of NotchCholangiopathyNovel treatmentsCyst growth
2015
Malignancies in Primary Sclerosing Cholangitis - A Continuing Threat
Bonato G, Cristoferi L, Strazzabosco M, Fabris L. Malignancies in Primary Sclerosing Cholangitis - A Continuing Threat. Digestive Diseases 2015, 33: 140-148. PMID: 26641079, PMCID: PMC4939833, DOI: 10.1159/000440826.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseUlcerative colitisEffective medical treatmentGallbladder carcinomaColorectal carcinomaUnknown etiologyEarly diagnosisMedical treatmentChronic inflammatory liver diseaseManagement of PSCInflammatory liver diseasePrimary sclerosing cholangitisGroup of patientsChronic inflammatory conditionsChronic inflammatory diseaseBile duct systemRisk of cancerDevelopment of malignancyEffective surveillance strategiesExtensive histologicLiver transplantationNeoadjuvant chemoradiotherapySclerosing cholangitisFeared complicationFrequent complication