Pathophysiologic implications of innate immunity and autoinflammation in the biliary epithelium
Strazzabosco M, Fiorotto R, Cadamuro M, Spirli C, Mariotti V, Kaffe E, Scirpo R, Fabris L. Pathophysiologic implications of innate immunity and autoinflammation in the biliary epithelium. Biochimica Et Biophysica Acta (BBA) - Molecular Basis Of Disease 2017, 1864: 1374-1379. PMID: 28754453, PMCID: PMC5785585, DOI: 10.1016/j.bbadis.2017.07.023.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsToll-like receptorsLiver damageCystic fibrosis-related liver diseaseInnate immunityDamage-associated molecular patternsEpithelial innate immunityPro-inflammatory behaviorBiliary epithelial cellsNumber of receptorsJesus BanalesMarco MarzioniNicholas LaRussoPeter JansenLiver injuryLiver diseaseBile flowInflammatory processBiliary epitheliumInflammatory responsePathophysiologic implicationsReparative processesNumber of evidencesFirst defense lineCholangiocytesMolecular patternsThe Healthy Biliary Tree: Cellular and Immune Biology
Cadamuro M, Fabris L, Strazzabosco M. The Healthy Biliary Tree: Cellular and Immune Biology. 2017, 17-41. DOI: 10.1007/978-3-319-50168-0_2.Peer-Reviewed Original ResearchBiliary innate immunityToll-like receptorsPathogen-associated molecular patternsBiliary treeLiver diseaseCystic fibrosis-related liver diseaseInnate immunityCystic fibrosis liver diseaseAntigen-presenting cellsBiliary epithelial cellsLiver injuryBile ductBiliary diseaseLiver damageInflammatory responseImmune biologyFirst defense lineProinflammatory behaviorSecretory activityMolecular patternsCholangiocytesEpithelial cellsDiseaseCholangiopathyEvidence highlights