Unmet needs in basic and translational research in Cholangiocarcinoma
Cadamuro M, Macias R, Strain A, Strazzabosco M, Simioni P, Marin J, Fabris L. Unmet needs in basic and translational research in Cholangiocarcinoma. Liver Cancer International 2021, 3: 5-16. DOI: 10.1002/lci2.39.Peer-Reviewed Original ResearchTranslational researchManagement of cholangiocarcinomaTumor-restraining functionsSystematic literature searchCCA managementPoor prognosisExtrahepatic cholangiocarcinomaDeep molecular phenotypingConsensus statementEnigmatic diseaseActionable mutationsCholangiocarcinomaAccurate biomarkersTumor microenvironmentLiterature searchExperimental modelEarly detectionMarked heterogeneityDiseaseMolecular phenotypingWide heterogeneityFurther studiesTumorsMolecular characterization studiesComplex role