2013
Notch signaling and new therapeutic options in liver disease
Morell CM, Strazzabosco M. Notch signaling and new therapeutic options in liver disease. Journal Of Hepatology 2013, 60: 885-890. PMID: 24308992, DOI: 10.1016/j.jhep.2013.11.028.Peer-Reviewed Original ResearchConceptsLiver diseaseTherapeutic agentsNew therapeutic optionsNotch signalingSpecific therapeutic agentsStem cell featuresTherapeutic optionsLiver malignanciesLiver metabolismTherapeutic relevanceAberrant activationLiver regenerationPersistent activationDiseaseAdult liverPossible targetsFurther studiesCell featuresNovel findingsRecent reportsNotch pathwayLiverCritical playersSignalingActivation
2010
Foxa1 and Foxa2 regulate bile duct development in mice
Strazzabosco M. Foxa1 and Foxa2 regulate bile duct development in mice. Journal Of Hepatology 2010, 52: 765-767. PMID: 20347503, PMCID: PMC2862815, DOI: 10.1016/j.jhep.2009.12.022.Peer-Reviewed Original ResearchIL-6 expressionBile duct developmentClinical investigationDuct developmentGlucocorticoid receptorBile duct expansionForkhead box protein A1American SocietyIL-6 promoterIL-6 transcriptionBiliary treeBile duct formationCholangiocyte proliferationConditional gene ablationGene ablationDevelopmental competenceLiverAdult liverDuct expansionEmbryonic liverProtein A1Liver specificationFOXA1MiceLate phase