Granular Cells as a Marker of Early Amiodarone Hepatotoxicity
Jain D, Bowlus C, Anderson J, Robert M. Granular Cells as a Marker of Early Amiodarone Hepatotoxicity. Journal Of Clinical Gastroenterology 2000, 31: 241-243. PMID: 11034006, DOI: 10.1097/00004836-200010000-00012.Peer-Reviewed Original ResearchConceptsChronic amiodarone useGranular cellsAmiodarone useAcute hepatitisAcute administrationLiver biopsyPathologic findingsIdiosyncratic reactionsAD therapyAmiodarone hepatotoxicityGranular cytoplasmHepatotoxicityClusters of cellsHepatitisMembranous inclusionsCellsBiopsyHistologicTherapyCliniciansLiverMacrophagesAdministrationWeeks