2004
Automated detection of immunofluorescently labeled cytomegalovirus‐infected cells in isolated peripheral blood leukocytes using decision tree analysis
Ladanyi A, Sher AC, Herlitz A, Bergsrud DE, Kraeft S, Kepros J, McDaid G, Ferguson D, Landry ML, Chen LB. Automated detection of immunofluorescently labeled cytomegalovirus‐infected cells in isolated peripheral blood leukocytes using decision tree analysis. Cytometry Part A 2004, 58A: 147-156. PMID: 15057968, DOI: 10.1002/cyto.a.20016.Peer-Reviewed Original ResearchConceptsPeripheral blood leukocytesBlood leukocytesPatient samplesDecision tree analysisImage cytometryCytomegalovirus-infected cellsCMV infectionCytomegalovirus infectionAntiviral therapyViral antigensCellular featuresCytospin preparationsLeukocytesInfectionCytometryManual microscopic analysisImage cytometerRare cellsCellsSimilar resultsPatientsCMVTherapyAntigenDiagnosis
2001
Evaluation of Biosite Triage Clostridium difficile Panel for Rapid Detection of Clostridium difficile in Stool Samples
Landry M, Topal J, Ferguson D, Giudetti D, Tang Y. Evaluation of Biosite Triage Clostridium difficile Panel for Rapid Detection of Clostridium difficile in Stool Samples. Journal Of Clinical Microbiology 2001, 39: 1855-1858. PMID: 11326003, PMCID: PMC88038, DOI: 10.1128/jcm.39.5.1855-1858.2001.Peer-Reviewed Original ResearchConceptsNegative predictive valuePositive predictive valueCommon antigenStool samplesPredictive valueC. difficile toxin AHigh negative predictive valueAntigen-positive patientsDifficile-negative patientsAntigen positive resultDifficile toxin ADifficile carriersContact precautionsAntibiotic treatmentToxin ACytotoxin titersTriage PanelUnnecessary useClostridium difficilePatients
2000
A Standardized Plaque Reduction Assay for Determination of Drug Susceptibilities of Cytomegalovirus Clinical Isolates
Landry M, Stanat S, Biron K, Brambilla D, Britt W, Jokela J, Chou S, Drew W, Erice A, Gilliam B, Lurain N, Manischewitz J, Miner R, Nokta M, Reichelderfer P, Spector S, Weinberg A, Yen-Lieberman B, Crumpacker C, Group T. A Standardized Plaque Reduction Assay for Determination of Drug Susceptibilities of Cytomegalovirus Clinical Isolates. Antimicrobial Agents And Chemotherapy 2000, 44: 688-692. PMID: 10681339, PMCID: PMC89747, DOI: 10.1128/aac.44.3.688-692.2000.Peer-Reviewed Original Research
1996
Interleukin-11: stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness.
Einarsson O, Geba G, Zhu Z, Landry M, Elias J. Interleukin-11: stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness. Journal Of Clinical Investigation 1996, 97: 915-924. PMID: 8613544, PMCID: PMC507136, DOI: 10.1172/jci118514.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusIL-11 productionParainfluenza virus type 3Airway hyperresponsivenessIL-11Viral upper respiratory tract infectionUpper respiratory tract infectionBALB/c miceSimplex virus type 2Viral-induced asthmaViral respiratory infectionsRespiratory tract infectionsNonspecific airway hyperresponsivenessVirus type 2Virus type 3Clinical bronchospasmAirway dysfunctionAirway physiologyTract infectionsRespiratory infectionsRespiratory virusesSyncytial virusC miceNasal aspiratesViral infectionRhinovirus stimulation of interleukin-6 in vivo and in vitro. Evidence for nuclear factor kappa B-dependent transcriptional activation.
Zhu Z, Tang W, Ray A, Wu Y, Einarsson O, Landry ML, Gwaltney J, Elias JA. Rhinovirus stimulation of interleukin-6 in vivo and in vitro. Evidence for nuclear factor kappa B-dependent transcriptional activation. Journal Of Clinical Investigation 1996, 97: 421-430. PMID: 8567963, PMCID: PMC507033, DOI: 10.1172/jci118431.Peer-Reviewed Original ResearchConceptsIL-6 productionIL-6RV infectionPotent stimulatorIL-6 protein productionIL-6 siteSymptomatic RV infectionsNuclear factor kappa BFactor kappa BIL-6 mRNA accumulationNF-kappa B activationNF-kappa B DNA binding activityPromoter-driven luciferase activityRhinovirus stimulationRV challengeNF-kappa BNF-kappa B siteInterleukin-6Nasal washingsKappa BSymptomatic volunteersRhinovirusStimulation pathwayNuclear factorB activation
1995
Interleukin‐11 in Respiratory Inflammation
EINARSSON O, GEBA GP, ZHOU Z, LANDRY ML, PANETTIERI RA, TRISTRAM D, WELLIVER R, METINKO A, ELIAS JA. Interleukin‐11 in Respiratory Inflammation. Annals Of The New York Academy Of Sciences 1995, 762: 89-101. PMID: 7668577, DOI: 10.1111/j.1749-6632.1995.tb32317.x.Peer-Reviewed Original Research
1994
Epithelial interleukin-11. Regulation by cytokines, respiratory syncytial virus, and retinoic acid.
Elias J, Zheng T, Einarsson O, Landry M, Trow T, Rebert N, Panuska J. Epithelial interleukin-11. Regulation by cytokines, respiratory syncytial virus, and retinoic acid. Journal Of Biological Chemistry 1994, 269: 22261-22268. PMID: 8071352, DOI: 10.1016/s0021-9258(17)31785-4.Peer-Reviewed Original ResearchMeSH KeywordsCells, CulturedCytokinesEpitheliumHumansInterleukin-11LungRespiratory Syncytial VirusesRNA, MessengerTretinoinConceptsRespiratory syncytial virusIL-11 productionIL-11 protein productionIL-1IL-11Retinoic acidSyncytial virusSimplex virus type 2Growth factorIL-11 mRNADose-dependent fashionVirus type 2Hepatocyte growth factorStimulus-specific fashionIL-6IL-4IL-7Alveolar A549 cellsPleiotropic cytokineType 2Human alveolar A549 cellsInterleukin-11Epithelial cellsA549 cellsUnstimulated cells
1991
Advantages of multiple cell culture systems for detection of mixed-virus infections
Fong C, Landry M. Advantages of multiple cell culture systems for detection of mixed-virus infections. Journal Of Virological Methods 1991, 33: 283-289. PMID: 1783674, DOI: 10.1016/0166-0934(91)90027-w.Peer-Reviewed Original ResearchConceptsMRC-5 cellsHSV-1MRC-5CMV-positive casesA549 cellsHSV-1 isolatesCell culturesRhesus monkey kidney cell culturesMonkey kidney cell culturesHuman continuous cell lineImmunosuppressed patientsCytomegalovirus antigenFibroblast cell strainsCentrifugation cultureKidney cell culturesViral agentsSimultaneous infectionContinuous cell linesCulture systemShell vialsMore virusesAdenovirus isolatesEmbryo cell culturesCell culture systemMixed virus infections
1987
Impact of cell culture sensitivity and virus concentration on rapid detection of herpes simplex virus by cytopathic effects and immunoperoxidase staining
Zhao LS, Landry ML, Balkovic ES, Hsiung GD. Impact of cell culture sensitivity and virus concentration on rapid detection of herpes simplex virus by cytopathic effects and immunoperoxidase staining. Journal Of Clinical Microbiology 1987, 25: 1401-1405. PMID: 3040800, PMCID: PMC269234, DOI: 10.1128/jcm.25.8.1401-1405.1987.Peer-Reviewed Original ResearchConceptsHerpes simplex virusSimplex virusCytopathic effectHerpes simplex virus (HSV) isolationMink lungVero cellsOverall isolation rateViral antigen detectionViral infectivity titerCell culturesApplication of immunoperoxidaseCommercial kitsMRC-5 cellsRapidity of detectionRabbit kidney cellsCulture sensitivityVirus isolationClinical specimensInfectious virusInfectivity titersHigh titersAntigen detectionIsolation rateImmunoperoxidaseRabbit kidney
1986
Comparison of in situ hybridization and immunologic staining with cytopathology for detection and identification of herpes simplex virus infection in cultured cells
Landry ML, Zibello TA, Hsiung GD. Comparison of in situ hybridization and immunologic staining with cytopathology for detection and identification of herpes simplex virus infection in cultured cells. Journal Of Clinical Microbiology 1986, 24: 968-971. PMID: 3023442, PMCID: PMC269080, DOI: 10.1128/jcm.24.6.968-971.1986.Peer-Reviewed Original Research
1984
Laboratory diagnosis of herpes simplex virus type 1 and type 2 infections
Hsiung GD, Landry ML, Mayo DR, Fong C. Laboratory diagnosis of herpes simplex virus type 1 and type 2 infections. Clinics In Dermatology 1984, 2: 67-82. PMID: 6100717, DOI: 10.1016/0738-081x(84)90067-1.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalAntibodies, ViralCells, CulturedCytopathogenic Effect, ViralDNA Restriction EnzymesFluorescent Antibody TechniqueHerpes GenitalisHerpes LabialisHerpes SimplexHumansImmunoenzyme TechniquesInclusion Bodies, ViralMicroscopy, ElectronNucleic Acid HybridizationSimplexvirusSpecimen HandlingVirionConceptsHerpes simplex virusHSV infectionHSV-2Virus isolationRecurrence of diseaseCommon viral infectionsEffective antiviral therapyType 2 infectionHerpes simplex virus type 1Simplex virus type 1HSV-1 infectionVirus type 1Fever blistersHSV isolationHerpetic lesionsAntiviral therapyClinical findingsGenital lesionsCommon manifestationDrug reactionsAllergic reactionsSevere diseaseGenital areaSimplex virusInfection results
1982
The need for a rapid and accurate viral diagnosis
Landry ML, Mayo DR, Hsiung GD. The need for a rapid and accurate viral diagnosis. Pharmacology & Therapeutics 1982, 18: 107-132. PMID: 6296887, DOI: 10.1016/0163-7258(82)90028-6.Peer-Reviewed Original Research