2013
Comparison of Simplexa Universal Direct PCR with Cytotoxicity Assay for Diagnosis of Clostridium difficile Infection: Performance, Cost, and Correlation with Disease
Landry ML, Ferguson D, Topal J. Comparison of Simplexa Universal Direct PCR with Cytotoxicity Assay for Diagnosis of Clostridium difficile Infection: Performance, Cost, and Correlation with Disease. Journal Of Clinical Microbiology 2013, 52: 275-280. PMID: 24226924, PMCID: PMC3911468, DOI: 10.1128/jcm.02545-13.Peer-Reviewed Original ResearchConceptsAntigen-negative samplesGDH antigenToxigenic C. difficileC. difficileGDH-positive samplesClostridium difficile infectionGlutamate dehydrogenase antigenToxin B geneSemisolid stoolsC. difficile toxin B geneDifficile testingChart reviewNosocomial transmissionDifficile infectionDifficile diseaseReal-time PCRClinical consequencesMerit further studyRapid molecular diagnosisDifficile bacteriaAntigenPatientsDehydrogenase antigenCost avoidanceCytotoxicity assays
2008
Real-time PCR compared to Binax NOW and cytospin-immunofluorescence for detection of influenza in hospitalized patients
Landry ML, Cohen S, Ferguson D. Real-time PCR compared to Binax NOW and cytospin-immunofluorescence for detection of influenza in hospitalized patients. Journal Of Clinical Virology 2008, 43: 148-151. PMID: 18639488, PMCID: PMC7173065, DOI: 10.1016/j.jcv.2008.06.006.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAntibodies, MonoclonalChildChild, PreschoolFluorescent Antibody Technique, DirectHospitalizationHumansImmunoassayInfantInfluenza A virusInfluenza B virusInfluenza, HumanMiddle AgedNasopharynxReagent Kits, DiagnosticReproducibility of ResultsReverse Transcriptase Polymerase Chain ReactionSensitivity and SpecificityTaq PolymeraseTime FactorsVirus CultivationYoung AdultConceptsHospitalized patientsTaqMan RT-PCRRT-PCRInfluenza ARapid flu testsDiagnosis of influenzaInfluenza-positive samplesDetection of influenzaReal-time RT-PCRInfluenza BInfluenza diagnosisPatient managementReal-time PCRMore accurate testsPatientsBinaxTrue positive samplesRapid testClinical samplesPositive samplesFurther studiesHospitalAccurate testInfluenzaDiagnosisProspective Study of Human Metapneumovirus Detection in Clinical Samples by Use of Light Diagnostics Direct Immunofluorescence Reagent and Real-Time PCR
Landry ML, Cohen S, Ferguson D. Prospective Study of Human Metapneumovirus Detection in Clinical Samples by Use of Light Diagnostics Direct Immunofluorescence Reagent and Real-Time PCR. Journal Of Clinical Microbiology 2008, 46: 1098-1100. PMID: 18184854, PMCID: PMC2268359, DOI: 10.1128/jcm.01926-07.Peer-Reviewed Original Research