1999
A Novel Sulfonylurea Receptor Family Member Expressed in the Embryonic Drosophila Dorsal Vessel and Tracheal System*
Nasonkin I, Alikasifoglu A, Ambrose C, Cahill P, Cheng M, Sarniak A, Egan M, Thomas P. A Novel Sulfonylurea Receptor Family Member Expressed in the Embryonic Drosophila Dorsal Vessel and Tracheal System*. Journal Of Biological Chemistry 1999, 274: 29420-29425. PMID: 10506204, DOI: 10.1074/jbc.274.41.29420.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsATP-Binding Cassette TransportersCloning, MolecularDrosophilaDrosophila ProteinsGene Expression Regulation, DevelopmentalGlyburideHumansIn Situ HybridizationMolecular Sequence DataOocytesPatch-Clamp TechniquesPhylogenyPotassium ChannelsPotassium Channels, Inwardly RectifyingReceptors, DrugRNA, MessengerSulfonylurea ReceptorsXenopus laevisConceptsDrosophila embryogenesisPotassium channel activityTracheal systemNovel Drosophila geneDrosophila dorsal vesselDorsal vesselABC transporter familyChannel activityReceptor family membersDrosophila genesGene duplicationPotassium channelsDrosophila systemTransporter familyGenetic approachesATP-sensitive potassium channel activityGenesFunctional studiesSulfonylurea receptorKir6.2 subunitEmbryogenesisATP-sensitive potassium channelsSURxSubunitsDistinctive sequence
1997
A functional CFTR-NBF1 is required for ROMK2-CFTR interaction
McNicholas C, Nason M, Guggino W, Schwiebert E, Hebert S, Giebisch G, Egan M. A functional CFTR-NBF1 is required for ROMK2-CFTR interaction. American Journal Of Physiology 1997, 273: f843-f848. PMID: 9374850, DOI: 10.1152/ajprenal.1997.273.5.f843.Peer-Reviewed Original ResearchAmino Acid SubstitutionAnimalsBase SequenceBinding SitesCystic Fibrosis Transmembrane Conductance RegulatorFemaleGlyburideMembrane PotentialsModels, MolecularMutagenesis, Site-DirectedOligodeoxyribonucleotidesOocytesPatch-Clamp TechniquesPotassium ChannelsPotassium Channels, Inwardly RectifyingProtein Structure, SecondaryRecombinant ProteinsXenopus laevis
1996
Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator.
McNicholas C, Guggino W, Schwiebert E, Hebert S, Giebisch G, Egan M. Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator. Proceedings Of The National Academy Of Sciences Of The United States Of America 1996, 93: 8083-8088. PMID: 8755607, PMCID: PMC38879, DOI: 10.1073/pnas.93.15.8083.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsChloride ChannelsCyclic AMP-Dependent Protein KinasesCystic Fibrosis Transmembrane Conductance RegulatorFemaleGlyburideKidneyMembrane PotentialsOocytesPatch-Clamp TechniquesPhosphorylationPotassium ChannelsPotassium Channels, Inwardly RectifyingSodium ChannelsXenopus laevis