Interchromosomal associations between alternatively expressed loci
Spilianakis CG, Lalioti MD, Town T, Lee GR, Flavell RA. Interchromosomal associations between alternatively expressed loci. Nature 2005, 435: 637-645. PMID: 15880101, DOI: 10.1038/nature03574.Peer-Reviewed Original ResearchMeSH KeywordsAllelesAnimalsCell NucleusCells, CulturedChromatinChromosome PositioningChromosomes, MammalianCytokinesDeoxyribonuclease IEnhancer Elements, GeneticGene Expression RegulationIn Situ Hybridization, FluorescenceInterferon-gammaInterleukinsLocus Control RegionMiceMice, Inbred C57BLPolymerase Chain ReactionPromoter Regions, GeneticRNA, MessengerTh1 CellsTh2 CellsTranscriptional ActivationConceptsLocus control regionTh2 locus control regionInterchromosomal interactionsDNase I hypersensitive sitesTh2 cytokine locusT cell fateEukaryotic genesIntrachromosomal interactionsChromatin conformationInterchromosomal associationsCytokine genesDifferent chromosomesGene activationSeparate chromosomesControl regionRegulatory regionsHypersensitive sitesCytokine locusTh2 cytokine genesChromosome 10Gene expressionPromoter regionChromosome 11GenesFunctional consequences