2008
Analytic Reviews: Considerations in Caring for the Critically Ill Older Patient
Pisani MA. Analytic Reviews: Considerations in Caring for the Critically Ill Older Patient. Journal Of Intensive Care Medicine 2008, 24: 83-95. PMID: 19114416, DOI: 10.1177/0885066608329942.Peer-Reviewed Original ResearchConceptsOlder patientsPhysiologic changesOlder intensive care unit patientsIntensive care unit admissionIntensive care unit patientsIll Older PatientsImportant physiologic changesOlder ICU patientsCare unit admissionCare unit patientsDevelopment of sepsisSeverity of illnessUnit admissionCritical illnessUnit patientsICU patientsPoor outcomeAdverse outcomesRisk factorsCritical careOutcome studiesChronologic agePatientsAge 65Sepsis
2007
Characteristics Associated With Delirium in Older Patients in a Medical Intensive Care Unit
Pisani MA, Murphy TE, Van Ness PH, Araujo KL, Inouye SK. Characteristics Associated With Delirium in Older Patients in a Medical Intensive Care Unit. JAMA Internal Medicine 2007, 167: 1629-1634. PMID: 17698685, DOI: 10.1001/archinte.167.15.1629.Peer-Reviewed Original ResearchConceptsAdmission risk factorsMedical record reviewIntensive care unitICU admissionRisk factorsOlder patientsRecord reviewCare unitMedical intensive care unitUrban university teaching hospitalOlder ICU patientsReceipt of benzodiazepinesConfusion Assessment MethodPatients 60 yearsProspective cohort studyLower arterial pHUniversity Teaching HospitalMain outcome measuresMultivariate logistic regressionDelirium durationICU deliriumCohort studyCreatinine levelsICU patientsArterial pH
2005
Detection of Delirium in the Intensive Care Unit: Comparison of Confusion Assessment Method for the Intensive Care Unit with Confusion Assessment Method Ratings
McNicoll L, Pisani MA, Ely EW, Gifford D, Inouye SK. Detection of Delirium in the Intensive Care Unit: Comparison of Confusion Assessment Method for the Intensive Care Unit with Confusion Assessment Method Ratings. Journal Of The American Geriatrics Society 2005, 53: 495-500. PMID: 15743296, DOI: 10.1111/j.1532-5415.2005.53171.x.Peer-Reviewed Original ResearchConceptsConfusion Assessment MethodIntensive care unitCAM-ICUICU patientsCare unitMini-Mental State ExaminationCAM-ICU methodFalse-negative ratingsOlder ICU patientsRate of deliriumDetection of deliriumUniversity Teaching HospitalCAM methodsDetailed cognitive testingLevel of consciousnessMedical ICUTeaching hospitalInterrater reliability testingState ExaminationPatientsDeliriumCAM criteriaMore deficitsCognitive testingICU
2003
Underrecognition of Preexisting Cognitive Impairment by Physicians in Older ICU Patients
Pisani MA, Redlich C, McNicoll L, Ely EW, Inouye SK. Underrecognition of Preexisting Cognitive Impairment by Physicians in Older ICU Patients. CHEST Journal 2003, 124: 2267-2274. PMID: 14665510, DOI: 10.1378/chest.124.6.2267.Peer-Reviewed Original ResearchConceptsOlder ICU patientsCognitive impairmentICU patientsPhysician recognitionUrban university teaching hospitalCross-sectional comparative studyBlessed Dementia Rating ScalePreexisting Cognitive ImpairmentIndependent risk factorMedical record abstractionUniversity Teaching HospitalCognitive impairment increasesDementia Rating ScaleMajority of casesMedical ICUPatient factorsRecord abstractionICU physiciansIntensive carePhysician interviewsRisk factorsTeaching hospitalSerious illnessICUInformant QuestionnaireDelirium in the Intensive Care Unit: Occurrence and Clinical Course in Older Patients
McNicoll L, Pisani MA, Zhang Y, Ely EW, Siegel MD, Inouye SK. Delirium in the Intensive Care Unit: Occurrence and Clinical Course in Older Patients. Journal Of The American Geriatrics Society 2003, 51: 591-598. PMID: 12752832, DOI: 10.1034/j.1600-0579.2003.00201.x.Peer-Reviewed Original ResearchConceptsConfusion Assessment MethodOccurrence of deliriumPost-ICU periodICU stayMedical intensive care unit patientsIntensive care unit patientsOlder ICU patientsDevelopment of deliriumHalf of patientsProspective cohort studyCare unit patientsMedical chart reviewNormal mental statusBaseline functional statusSeverity of illnessIntensive care unitUniversity Teaching HospitalSurrogate interviewsHospital stayBaseline characteristicsChart reviewCohort studyFrequent complicationMedical ICUOlder patients