2016
Outcomes of Older Adults With Sepsis at Admission to an Intensive Care Unit
Rowe T, Araujo KL, Van Ness PH, Pisani MA, Juthani-Mehta M. Outcomes of Older Adults With Sepsis at Admission to an Intensive Care Unit. Open Forum Infectious Diseases 2016, 3: ofw010. PMID: 26925430, PMCID: PMC4766385, DOI: 10.1093/ofid/ofw010.Peer-Reviewed Original ResearchAssociation of sepsisICU admissionOlder adultsBaseline characteristicsSystemic inflammatory response syndrome criteriaIntensive care unit admissionCox proportional hazards modelImpact of sepsisCare unit admissionProspective cohort studyDiagnosis of sepsisDefinition of sepsisIntensive care unitMain outcome measuresProportional hazards modelUnit admissionSyndrome criteriaCohort studyCare unitOutcome measuresSepsisHazards modelAdmissionMortalityEarly use
2015
Comparing clinical outcomes in HIV‐infected and uninfected older men hospitalized with community‐acquired pneumonia
Barakat LA, Juthani-Mehta M, Allore H, Trentalange M, Tate J, Rimland D, Pisani M, Akgün KM, Goetz MB, Butt AA, Rodriguez-Barradas M, Duggal M, Crothers K, Justice AC, Quagliarello VJ. Comparing clinical outcomes in HIV‐infected and uninfected older men hospitalized with community‐acquired pneumonia. HIV Medicine 2015, 16: 421-430. PMID: 25959543, PMCID: PMC5015437, DOI: 10.1111/hiv.12244.Peer-Reviewed Original ResearchConceptsCommunity-acquired pneumoniaVeterans Aging Cohort StudyVACS IndexCAP outcomesAntiretroviral therapyOlder adultsHigher VACS indexDays of dischargeAging Cohort StudyUninfected participantsCohort studyMean LOSHIV infectionLonger LOSClinical outcomesUnadjusted analysesUninfected groupMultivariable modelEligibility criteriaHIVMale veteransMortality rateART useMortalityOutcomesMortality among patients with pleural effusion undergoing thoracentesis
DeBiasi EM, Pisani MA, Murphy TE, Araujo K, Kookoolis A, Argento AC, Puchalski J. Mortality among patients with pleural effusion undergoing thoracentesis. European Respiratory Journal 2015, 46: 495-502. PMID: 25837039, PMCID: PMC4857137, DOI: 10.1183/09031936.00217114.Peer-Reviewed Original ResearchConceptsCongestive heart failurePleural effusionRenal failureHeart failureBenign etiologyMalignant effusionsHigh mortalityBilateral pleural effusionLong-term mortalityMortality of patientsProspective cohort studyMalignant pleural effusionBaseline characteristicsChart reviewCohort studyNonmalignant effusionsPoor prognosisHigh riskPatientsEffusionStandardised criteriaThoracentesisMortalityEtiologyFailure
2014
Mortality of Hospitalized Patients with Pleural Effusions
Kookoolis AS, Puchalski JT, Murphy TE, Araujo KL, Pisani MA. Mortality of Hospitalized Patients with Pleural Effusions. Journal Of Pulmonary & Respiratory Medicine 2014, 4: 184. PMID: 25977841, PMCID: PMC4428160, DOI: 10.4172/2161-105x.1000184.Peer-Reviewed Original ResearchSeverity of illnessShort-term survival benefitPleural effusionSurvival benefitPulmonary diseaseYale-New Haven HospitalTerm survival benefitMedical servicesCause mortalityHazard ratioHospital admissionHospitalized patientsMedical patientsMalignant effusionsMedical recordsMedical populationsProtective effectHigh riskPatientsEffusionThoracentesesLarger studyMortalityIllnessOne-year
2012
Epidemiology and Management of Common Pulmonary Diseases in Older Persons
Akgün KM, Crothers K, Pisani M. Epidemiology and Management of Common Pulmonary Diseases in Older Persons. The Journals Of Gerontology Series A 2012, 67A: 276-291. PMID: 22337938, PMCID: PMC3297767, DOI: 10.1093/gerona/glr251.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdenocarcinoma of LungAgedAged, 80 and overAnti-Bacterial AgentsAnti-Inflammatory AgentsAntineoplastic AgentsAsthmaFemaleHumansIdiopathic Pulmonary FibrosisIncidenceLung DiseasesLung NeoplasmsMalePneumoniaPrevalencePulmonary Disease, Chronic ObstructiveRisk FactorsTreatment OutcomeConceptsOlder patientsPulmonary diseaseCommon pulmonary diseasesQuality of lifePulmonary symptomsChronic obstructive pulmonary diseaseCommon clinical presentationObstructive pulmonary diseaseIdiopathic pulmonary fibrosisCommon pulmonary disordersMedical comorbiditiesClinical presentationPulmonary fibrosisLung cancerMultiple etiologiesPulmonary disordersRisk factorsPrevalence increasesDisease prevalence increasesPatientsOlder personsDiseaseMortalityDyspneaComorbidities
2011
Critical Illness in HIV-Infected Patients in the Era of Combination Antiretroviral Therapy
Akgün KM, Huang L, Morris A, Justice AC, Pisani M, Crothers K. Critical Illness in HIV-Infected Patients in the Era of Combination Antiretroviral Therapy. Annals Of The American Thoracic Society 2011, 8: 301-307. PMID: 21653532, PMCID: PMC3132789, DOI: 10.1513/pats.201009-060wr.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyAntiretroviral therapyICU admissionCritical illnessAdministration of ARTImpact of ARTProportion of deathsHIV eraOpportunistic infectionsHIVAIDS epidemicMore recent studiesIllnessPatientsAdmissionTherapyRecent studiesICUEtiologyInfectionMortalityIncidenceDiseaseAdministration