2018
Atomoxetine for amphetamine-type stimulant dependence during buprenorphine treatment: A randomized controlled trial
Schottenfeld RS, Chawarski MC, Sofuoglu M, Chooi WT, Zaharim NM, M Yasin MA, Ahmad I, Syed Jaapar SZ, Vicknasingam BK. Atomoxetine for amphetamine-type stimulant dependence during buprenorphine treatment: A randomized controlled trial. Drug And Alcohol Dependence 2018, 186: 130-137. PMID: 29573648, PMCID: PMC5911201, DOI: 10.1016/j.drugalcdep.2018.01.017.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic Uptake InhibitorsAdultAmphetamine-Related DisordersAtomoxetine HydrochlorideBehavior TherapyBuprenorphineBuprenorphine, Naloxone Drug CombinationDepressionDouble-Blind MethodHumansMaleMiddle AgedNarcotic AntagonistsOpioid-Related DisordersPilot ProjectsTreatment OutcomeYoung AdultConceptsATS use disorderPlacebo-treated participantsUse disordersAdverse eventsUrine testsPotential efficacyAmphetamine-type stimulant dependenceAmphetamine-type stimulant useSerious adverse eventsBuprenorphine/naloxoneBetween-group differencesATS dependenceClinical tolerabilityMedication discontinuationBuprenorphine treatmentPrimary outcomeOpioid dependenceClinical trialsITT sampleTreat sampleBehavioral counselingDepressive symptomsDays abstinentAtomoxetineStimulant dependence
2017
Early Initiation of Amphetamine-Type Stimulants (ATS) Use Associated with Lowered Cognitive Performance among Individuals with Co-Occurring Opioid and ATS Use Disorders in Malaysia
Chooi WT, Zaharim N, Desrosiers A, Ahmad I, Yasin MAM, Jaapar S, Schottenfeld RS, Vicknasingam BK, Chawarski MC. Early Initiation of Amphetamine-Type Stimulants (ATS) Use Associated with Lowered Cognitive Performance among Individuals with Co-Occurring Opioid and ATS Use Disorders in Malaysia. Journal Of Psychoactive Drugs 2017, 49: 326-332. PMID: 28661714, PMCID: PMC6218246, DOI: 10.1080/02791072.2017.1342152.Peer-Reviewed Original ResearchConceptsCognitive performanceStandard Progressive MatricesRey-Osterrieth Complex Figure TestSymbol digit substitution taskCognitive performance groupsComplex Figure TestRaven's Standard Progressive MatricesATS use disorderATS useDigit spanTrail MakingCognitive functioningFigures TestAmphetamine-type stimulant useSubstitution taskProgressive MatricesFunctioning profilesDrug useCo-occurring opioidGroup differencesCurrent study findingsStimulant useClusters of individualsATS dependenceUse disorders