2024
Substance use and spine density: a systematic review and meta-analysis of preclinical studies
Oliva H, Prudente T, Nunes E, Cosgrove K, Radhakrishnan R, Potenza M, Angarita G. Substance use and spine density: a systematic review and meta-analysis of preclinical studies. Molecular Psychiatry 2024, 29: 2873-2885. PMID: 38561468, DOI: 10.1038/s41380-024-02519-3.Peer-Reviewed Original ResearchSpine densityPrefrontal cortexSubstance useDrug self-administrationHippocampal spine densityEffects of cocaineSubstance use disordersConvergence of findingsSpine density changesSubstances of abuseMeta-analysis of preclinical studiesNucleus accumbensBehavioral sensitizationSelf-administrationBrain mechanismsPreclinical studiesBrain regionsMorphine effectsSynaptic density changesMeta-analysisAmphetamineSynaptic densityCocaineModerate-to-highCortex
2023
Changes in synaptic markers after administration of ketamine or psychedelics: a systematic scoping review
Zhornitsky S, Oliva H, Jayne L, Allsop A, Kaye A, Potenza M, Angarita G. Changes in synaptic markers after administration of ketamine or psychedelics: a systematic scoping review. Frontiers In Psychiatry 2023, 14: 1197890. PMID: 37435405, PMCID: PMC10331617, DOI: 10.3389/fpsyt.2023.1197890.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAdministration of ketamineSynaptic markersSubstance use disordersPrefrontal cortexSingle doseBasal conditionsStress-related reductionPsilocybin/psilocinVerbal memory performanceWeb of ScienceKetamine treatmentSystematic scoping reviewLysergic acid diethylamideSynaptic densityClinical studiesSynaptophysin 1PRISMA guidelinesSynapsin 1Use disordersPlace preferenceAbuse liabilitySynaptic changesKetaminePSD-95Study design