Anandamide and 2-arachidonoylglycerol baseline plasma concentrations and their clinical correlate in gambling disorder
Baenas I, Solé-Morata N, Granero R, Fernández-Aranda F, Pujadas M, Mora-Maltas B, Lucas I, Gómez-Peña M, Moragas L, del Pino-Gutiérrez A, Tapia J, de la Torre R, Potenza M, Jiménez-Murcia S. Anandamide and 2-arachidonoylglycerol baseline plasma concentrations and their clinical correlate in gambling disorder. European Psychiatry 2023, 66: e97. PMID: 37937379, PMCID: PMC10755577, DOI: 10.1192/j.eurpsy.2023.2460.Peer-Reviewed Original ResearchConceptsHealthy control subjectsPlasma concentrationsBaseline plasma concentrationsPeripheral blood samplesBrain reward pathwaysGambling disorderSemi-structured clinical interviewConcentrations of endocannabinoidsNeuropsychological variablesAddiction-related disordersGD severityClinical correlatesControl subjectsAdult outpatientsEndocannabinoid systemBlood samplesClinical InterviewPlasma AEA concentrationsEndogenous ligandReward pathwayClinical groupsEndocannabinoidsAEA concentrationsPsychometric assessmentNeurobiological substratesPlasma concentration of leptin is related to food addiction in gambling disorder: Clinical and neuropsychological implications
Etxandi M, Baenas I, Mora-Maltas B, Granero R, Fernández-Aranda F, Tovar S, Solé-Morata N, Lucas I, Casado S, Gómez-Peña M, Moragas L, del Pino-Gutiérrez A, Tapia J, Valenciano-Mendoza E, Potenza M, Gearhardt A, Diéguez C, Jiménez-Murcia S. Plasma concentration of leptin is related to food addiction in gambling disorder: Clinical and neuropsychological implications. Journal Of Behavioral Addictions 2023, 12: 1019-1031. PMID: 38141066, PMCID: PMC10786224, DOI: 10.1556/2006.2023.00051.Peer-Reviewed Original ResearchConceptsBody mass indexLeptin concentrationsFood addictionPlasma concentrationsHigher body mass indexAppetite-regulating hormonesYale Food Addiction Scale 2.0Gambling disorderSemi-structured clinical interviewLiver-expressed antimicrobial peptide 2Clinical featuresMass indexAppetite regulationHormonal variablesBlood samplesLifetime diagnosisPatientsAntimicrobial peptide 2Clinical InterviewNeuropsychological featuresPoor inhibitory controlAnthropometric variablesEndocrine measuresHormonal concentrationsLeptin