Mutations in β-Spectrin Disrupt Axon Outgrowth and Sarcomere Structure
Hammarlund M, Davis W, Jorgensen E. Mutations in β-Spectrin Disrupt Axon Outgrowth and Sarcomere Structure. Journal Of Cell Biology 2000, 149: 931-942. PMID: 10811832, PMCID: PMC2174563, DOI: 10.1083/jcb.149.4.931.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAxonsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell MembraneCell PolarityDNA PrimersDNA, ComplementaryEpithelial CellsGenes, HelminthGenes, ReporterGreen Fluorescent ProteinsIntestinesIntracellular MembranesLuminescent ProteinsMolecular Sequence DataMutationSarcomeresSequence Homology, Amino AcidSpectrinSynaptic VesiclesConceptsCell polarityBeta spectrinMembrane skeletonCell membraneCaenorhabditis elegans homologueMost animal cellsSpecific membrane proteinsMembrane integrityAxon outgrowthNull mutantsMembrane proteinsAnimal cellsAbnormal axon outgrowthPlasma membraneSarcomere structureProteinDense bodiesMembraneOutgrowthMajor componentMyofilament latticeMutantsHomologuesGenesPolarity