Multiparametric magnetic resonance imaging shows promising results to assess renal transplant dysfunction with fibrosis
Bane O, Hectors S, Gordic S, Kennedy P, Wagner M, Weiss A, Khaim R, Yi Z, Zhang W, Delaney V, Salem F, He C, Menon MC, Lewis S, Taouli B. Multiparametric magnetic resonance imaging shows promising results to assess renal transplant dysfunction with fibrosis. Kidney International 2019, 97: 414-420. PMID: 31874802, PMCID: PMC6983343, DOI: 10.1016/j.kint.2019.09.030.Peer-Reviewed Original ResearchConceptsCortical apparent diffusion coefficientApparent diffusion coefficientChronic dysfunctionMedullary apparent diffusion coefficientsProspective single-center studyFractional anisotropyMultiparametric magnetic resonance imagingRenal allograft histologyRenal transplant dysfunctionTubular atrophy scoreRenal allograft dysfunctionRenal transplant patientsSingle-center studyMagnetic resonance imaging protocolIntravoxel incoherent motion diffusion-weighted imagingNon-invasive assessmentTest-retest repeatabilityMagnetic resonance imagingDiffusion-weighted imagingBlood oxygen levelDiffusion tensor imagingInter-observer reproducibilityAllograft dysfunctionAllograft histologyEGFR decline