2023
Ventricular Arrhythmia in Cancer Patients: Mechanisms, Treatment Strategies and Future Avenues
Agarwal M, Sridharan A, Pimentel R, Markowitz S, Rosenfeld L, Fradley M, Yang E. Ventricular Arrhythmia in Cancer Patients: Mechanisms, Treatment Strategies and Future Avenues. Arrhythmia & Electrophysiology Review 2023, 12: e16. PMID: 37457438, PMCID: PMC10345968, DOI: 10.15420/aer.2023.04.Peer-Reviewed Original ResearchVentricular arrhythmiasCancer treatmentOverall care of patientsCare of patientsInterruption of cancer treatmentNovel cancer treatmentsOverall careQTc prolongationCardiovascular complicationsImprove prognosisRepolarisation abnormalitiesVentricular conductionTreatment strategiesCancer patientsCancer therapyCardiovascular diseaseCancerArrhythmiasPatientsTreatmentQTcComplicationsPrognosis
2015
Outcomes of patients with definite and suspected isolated cardiac sarcoidosis treated with an implantable cardiac defibrillator
Kron J, Sauer W, Mueller G, Schuller J, Bogun F, Sarsam S, Rosenfeld L, Mitiku TY, Cooper JM, Mehta D, Greenspon AJ, Ortman M, Delurgio DB, Valadri R, Narasimhan C, Swapna N, Singh JP, Danik S, Markowitz SM, Almquist AK, Krahn AD, Wolfe LG, Feinstein S, Ellenbogen KA, Crawford T. Outcomes of patients with definite and suspected isolated cardiac sarcoidosis treated with an implantable cardiac defibrillator. Journal Of Interventional Cardiac Electrophysiology 2015, 43: 55-64. PMID: 25676929, DOI: 10.1007/s10840-015-9978-3.Peer-Reviewed Original ResearchConceptsCardiac magnetic resonanceImplantable cardiac defibrillatorPositron emission tomographyAppropriate ICD therapyAnti-tachycardia pacingICD therapyCardiac defibrillatorLeft ventricular ejection fractionAppropriate ICD interventionsSecondary prevention indicationTrue natural historyOutcomes of patientsMulticenter retrospective reviewVentricular ejection fractionEnhanced cardiac CTExtracardiac sarcoidosisICD interventionsCardiac sarcoidosisPrevention indicationConsecutive patientsEjection fractionHeart transplantRetrospective reviewSarcoidosis patientsVentricular arrhythmias
1996
Initial Single‐Center Experience with an Advanced Third‐Generation Investigational Defibrillator
LAMPERT R, ROSENFELD L, McPHERSON C, LEWIS R, VANZETTA A, BATSFORD W. Initial Single‐Center Experience with an Advanced Third‐Generation Investigational Defibrillator. Pacing And Clinical Electrophysiology 1996, 19: 2072-2082. PMID: 8994946, DOI: 10.1111/j.1540-8159.1996.tb03281.x.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillatorDefibrillation thresholdInitial single-center experienceYale-New Haven HospitalShocking electrodesSingle-center experienceLow-energy biphasic shocksBiphasic defibrillation thresholdLower defibrillation thresholdInappropriate therapyVentricular arrhythmiasVT zoneNonthoracotomy implantationCardioverter defibrillatorEffective treatmentVF zoneAV dissociationTransvenous systemsPatientsAvailable electrogramsNoninvasive electrophysiologyRR intervalsEPS resultsTherapyBiphasic shocks
1992
Determinants of the hemodynamic consequence to sustained ventricular arrhythmias after a single myocardial infarction
Sager P, Perlmutter R, Rosenfeld L, Batsford W. Determinants of the hemodynamic consequence to sustained ventricular arrhythmias after a single myocardial infarction. American Heart Journal 1992, 124: 1484-1491. PMID: 1462903, DOI: 10.1016/0002-8703(92)90061-y.Peer-Reviewed Original ResearchConceptsProportion of patientsSustained ventricular tachycardiaStable sustained ventricular tachycardiaSustained ventricular arrhythmiasMyocardial infarctionCardiac arrestSingle myocardial infarctionVentricular arrhythmiasVentricular tachycardiaHemodynamic consequencesCA groupGlobal left ventricular ejection fractionLeft ventricular ejection fractionCongestive heart failureVentricular ejection fractionCoronary artery diseasePrevious myocardial infarctionAnterior wall infarctionBundle branch blockInferior wall infarctionArrhythmic cardiac arrestArtery diseaseEjection fractionHeart failureElectrophysiologic studyStrategies in the Surgical Treatment of Malignant Ventricular Arrhythmias An 8-year Experience
GEHA A, ELEFTERIADES J, HSU J, BIBLO L, HOCH D, BATSFORD W, ROSENFELD L, CARLSON M, JOHNSON N, WALDO A. Strategies in the Surgical Treatment of Malignant Ventricular Arrhythmias An 8-year Experience. Annals Of Surgery 1992, 216: 309-317. PMID: 1417180, PMCID: PMC1242614, DOI: 10.1097/00000658-199209000-00010.Peer-Reviewed Original ResearchConceptsAutomatic implantable cardioverter defibrillatorSubendocardial resectionVentricular tachycardiaSurgical treatmentLV aneurysmSudden deathThirty-day mortality rateSevere LV dysfunctionCongestive heart failureRecurrent ventricular tachycardiaSignificant myocardial ischemiaLong-term survivorsMalignant ventricular arrhythmiasMalignant ventricular tachyarrhythmiasCent of survivorsImplantable cardioverter defibrillatorLong-term survivalActuarial survivalAntiarrhythmic medicationsLate deathsComparable patientsLV dysfunctionConsecutive patientsHeart failureVentricular arrhythmiasAntiarrhythmic drug exacerbation of ventricular tachycardia inducibility during electrophysiologic study
Sager P, Perlmutter R, Rosenfeld L, Batsford W. Antiarrhythmic drug exacerbation of ventricular tachycardia inducibility during electrophysiologic study. American Heart Journal 1992, 123: 926-933. PMID: 1550002, DOI: 10.1016/0002-8703(92)90698-u.Peer-Reviewed Original ResearchConceptsTest-negative groupInducible ventricular tachycardiaTest positive groupVentricular tachycardiaElectrophysiologic studyVentricular arrhythmiasClinical characteristicsSignificant organic heart diseaseInducible sustained ventricular tachycardiaDrug-induced exacerbationGroups' clinical characteristicsInducible ventricular arrhythmiasDrug testsVentricular ejection fractionVentricular tachycardia inductionOrganic heart diseaseSustained ventricular tachycardiaBundle branch blockDrug-free stateVentricular tachycardia inducibilityTachycardia inductionAntiarrhythmic therapyInducible arrhythmiasEjection fractionVentricular aneurysmTachycardias of Right Ventricular Origin
Hoch D, Rosenfeld L. Tachycardias of Right Ventricular Origin. Cardiology Clinics 1992, 10: 151-164. PMID: 1739956, DOI: 10.1016/s0733-8651(18)30260-1.Peer-Reviewed Original ResearchConceptsRight ventricular dysplasiaRight ventricular outflow tractRepetitive monomorphic ventricular tachycardiaRight ventricular arrhythmiasRepair of tetralogyVentricular outflow tractMonomorphic ventricular tachycardiaVentricular arrhythmiasVentricular tachycardiaVentricular dysplasiaRight ventricleClinical entityCatheter manipulationOutflow tractRight ventricular outflow tract tachycardiaIsolated right ventricular infarctionVentricular outflow tract tachycardiaExercise-induced ventricular tachycardiaLeft bundle branch morphologyAbnormal right ventricleRight heart dilatationRight ventricular incisionRight ventricular ischemiaOutflow tract tachycardiaRight ventricular infarction
1990
Evolving patterns in the surgical treatment of malignant ventricular tachyarrhythmias
Elefteriades J, Biblo L, Batsford W, Rosenfeld L, Henthorn R, Carlson M, Waldo A, Hsu J, Geha A. Evolving patterns in the surgical treatment of malignant ventricular tachyarrhythmias. The Annals Of Thoracic Surgery 1990, 49: 94-100. PMID: 2297279, DOI: 10.1016/0003-4975(90)90362-a.Peer-Reviewed Original ResearchConceptsAutomatic implantable cardioverter defibrillatorResection groupThirty-day mortalityCoronary artery bypassMalignant ventricular tachyarrhythmiasIntractable ventricular arrhythmiasImplantable cardioverter defibrillatorAICD placementArtery bypassSurgical treatmentEndocardial resectionVentricular arrhythmiasVentricular tachyarrhythmiasAntiarrhythmic agentsSudden deathCardioverter defibrillatorResectionMortality figuresPatientsEffective interventionsGreatest overall benefitSurvivalGroupOverall benefitValuable alternative
1989
Rapid self-terminating ventricular tachycardia induced during electrophysiologic study: A prospective evaluation
Sager P, Perlmutter R, Rosenfeld L, McPherson C, Batsford W. Rapid self-terminating ventricular tachycardia induced during electrophysiologic study: A prospective evaluation. Journal Of The American College Of Cardiology 1989, 13: 385-390. PMID: 2913116, DOI: 10.1016/0735-1097(89)90516-0.Peer-Reviewed Original ResearchConceptsGroup B patientsSelf-terminating ventricular tachycardiaGroup A patientsB patientsGroup C patientsVentricular tachycardiaA patientsC patientsElectrophysiologic studyGroup ALeft ventricular ejection fractionClinical ventricular arrhythmiasVentricular ejection fractionCoronary artery diseaseStructural heart diseaseSustained ventricular tachycardiaInduced ventricular tachycardiaClinical characteristicsArtery diseaseEjection fractionVentricular arrhythmiasPatient groupProspective evaluationElectrophysiologic characteristicsHeart disease
1988
Device Therapy of Ventricular Tachyarrhythmias
Rosenfeld L. Device Therapy of Ventricular Tachyarrhythmias. Cardiology Clinics 1988, 6: 437-448. PMID: 3073009, DOI: 10.1016/s0733-8651(18)30487-9.Peer-Reviewed Original ResearchConceptsDevice therapyLife-threatening ventricular arrhythmiasConcomitant antiarrhythmic therapyMajority of patientsManagement of patientsAntitachycardia devicesAntiarrhythmic therapyPatient selectionVentricular arrhythmiasVentricular tachyarrhythmiasVentricular fibrillationAntitachycardia pacemakerDefibrillation capabilitySuch drugsTherapyPatientsElectrophysiologic effects of thrombolytic therapy in patients with a transmural anterior myocardial infarction complicated by left ventricular aneurysm formation
Sager P, Perlmutter R, Rosenfeld L, McPherson C, Wackers F, Batsford W. Electrophysiologic effects of thrombolytic therapy in patients with a transmural anterior myocardial infarction complicated by left ventricular aneurysm formation. Journal Of The American College Of Cardiology 1988, 12: 19-24. PMID: 3379204, DOI: 10.1016/0735-1097(88)90350-6.Peer-Reviewed Original ResearchConceptsGroup B patientsLeft ventricular aneurysm formationTransmural anterior myocardial infarctionGroup A patientsVentricular aneurysm formationAnterior myocardial infarctionThrombolytic therapyB patientsVentricular tachycardiaA patientsVentricular arrhythmiasMyocardial infarctionAneurysm formationNew bundle branch blockPeak creatine kinase-MB levelsLeft ventricular ejection fractionCreatine kinase-MB levelsClinical arrhythmic eventsEarly thrombolytic therapyCongestive heart failureVentricular ejection fractionSustained ventricular tachycardiaInduced ventricular arrhythmiasBundle branch blockPostmyocardial infarction patients
1986
Ventricular tachycardia induction: Comparison of triple extrastimuli with an abrupt change in ventricular drive cycle length
Rosenfeld L, McPherson C, Kennedy E, Stark S, Batsford W. Ventricular tachycardia induction: Comparison of triple extrastimuli with an abrupt change in ventricular drive cycle length. American Heart Journal 1986, 111: 868-874. PMID: 3706105, DOI: 10.1016/0002-8703(86)90635-6.Peer-Reviewed Original ResearchConceptsRight ventricular apexDouble extrastimuliTriple extrastimuliVentricular arrhythmiasVentricular tachycardiaVentricular apexCycle lengthSerial drug testingGroup III patientsDrive cycle lengthSustained ventricular tachycardiaIndwelling catheterIII patientsClinical arrhythmiaLow suspicionStimulation protocolTachycardiaExtrastimuliPatientsGroup IArrhythmiasDrug testingCatheterFibrillationSuspicion